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  1. Non-muscle invasive bladder cancer (NMIBC) is a major type of bladder cancer with a high incidence worldwide, resulting in a great disease burden. Treatment and surveillance are the most important part of NIMB...

    Authors: Ying-Hui Jin, Xian-Tao Zeng, Tong-Zu Liu, Zhi-Ming Bai, Zhong-Ling Dou, De-Gang Ding, Zhi-Lu Fan, Ping Han, Yi-Ran Huang, Xing Huang, Ming Li, Xiao-Dong Li, Yi-Ning Li, Xu-Hui Li, Chao-Zhao Liang, Jiu-Min Liu…
    Citation: Military Medical Research 2022 9:44
  2. Extracellular RNAs (exRNAs) are novel circulating factors that can be used as biomarkers in various diseases. Their unique and diverse kinds, as well as their role as biomarkers, make them significant biomarke...

    Authors: Abdullah Muhammad Sohail, Muhammad Babar Khawar, Ali Afzal, Ali Hassan, Sara Shahzaman and Ahmed Ali
    Citation: Military Medical Research 2022 9:43
  3. Cholangiocarcinoma (CHOL) is one of the most aggressive tumors worldwide and cannot be effectively treated by conventional and novel treatments, including immune checkpoint blockade therapy. The mRNA vaccine-b...

    Authors: Tian-Yu Tang, Xing Huang, Gang Zhang, Ming-Hao Lu and Ting-Bo Liang
    Citation: Military Medical Research 2022 9:40
  4. Autophagy dysfunction plays a crucial role in tau accumulation and neurodegeneration in Alzheimer’s disease (AD). This study aimed to investigate whether and how the accumulating tau may in turn affect autophagy.

    Authors: Meng-Zhu Li, En-Jie Liu, Qiu-Zhi Zhou, Shi-Hong Li, Shi-Jie Liu, Hai-Tao Yu, Qi-Hang Pan, Fei Sun, Ting He, Wei-Jin Wang, Dan Ke, Yu-Qi Feng, Jun Li and Jian-Zhi Wang
    Citation: Military Medical Research 2022 9:38
  5. Traumatic colon injury (TCI) is a common disease during wartime. Prolongation of posttraumatic survival time is an effective approach to patient outcome improvement. However, there is a lack of basic research ...

    Authors: Bo Cao, Rui-Yang Zhao, Hang-Hang Li, Xing-Ming Xu, Hao Cui, Huan Deng, Lin Chen and Bo Wei
    Citation: Military Medical Research 2022 9:37
  6. The literature is full of claims regarding the consumption of polyphenol or polyamine-rich foods that offer some protection from developing cardiovascular disease (CVD). This is achieved by preventing cardiac ...

    Authors: Lei Pang, Xi Jiang, Xin Lian, Jie Chen, Er-Fei Song, Lei-Gang Jin, Zheng-Yuan Xia, Hai-Chun Ma and Yin Cai
    Citation: Military Medical Research 2022 9:33
  7. Due to the outbreak and rapid spread of coronavirus disease 2019 (COVID-19), more than 160 million patients have become convalescents worldwide to date. Significant alterations have occurred in the gut and ora...

    Authors: Guang-Ying Cui, Ben-Chen Rao, Zhao-Hai Zeng, Xue-Mei Wang, Tong Ren, Hai-Yu Wang, Hong Luo, Hong-Yan Ren, Chao Liu, Su-Ying Ding, Jun-Jie Tan, Zhen-Guo Liu, Ya-Wen Zou, Zhi-Gang Ren and Zu-Jiang Yu
    Citation: Military Medical Research 2022 9:32
  8. Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indi...

    Authors: Peng Gao, Yan-Qing Liu, Wei Xiao, Fei Xia, Jia-Yun Chen, Li-Wei Gu, Fan Yang, Liu-Hai Zheng, Jun-Zhe Zhang, Qian Zhang, Zhi-Jie Li, Yu-Qing Meng, Yong-Ping Zhu, Huan Tang, Qiao-Li Shi, Qiu-Yan Guo…
    Citation: Military Medical Research 2022 9:30
  9. Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is associated with poor prognosis. Its characteristics of being highly invasive and undergoing heterogeneous genetic mutat...

    Authors: Qing-Long Guo, Xing-Liang Dai, Meng-Yuan Yin, Hong-Wei Cheng, Hai-Sheng Qian, Hua Wang, Dao-Ming Zhu and Xian-Wen Wang
    Citation: Military Medical Research 2022 9:26
  10. Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that can occur when the blood supply to the ischemic brain tissue is restored. However, the mechanism underlying such injury remai...

    Authors: Xue Zeng, Yun-Dong Zhang, Rui-Yan Ma, Yuan-Jing Chen, Xin-Ming Xiang, Dong-Yao Hou, Xue-Han Li, He Huang, Tao Li and Chen-Yang Duan
    Citation: Military Medical Research 2022 9:25
  11. Mucosal-associated invariant T (MAIT) cells are systemically depleted in human immunodeficiency virus type 1 (HIV-1) infected patients and are not replenished even after successful combined antiretroviral ther...

    Authors: Peng Xia, Xu-Dong Xing, Cui-Xian Yang, Xue-Jiao Liao, Fu-Hua Liu, Hui-Huang Huang, Chao Zhang, Jin-Wen Song, Yan-Mei Jiao, Ming Shi, Tian-Jun Jiang, Chun-Bao Zhou, Xi-Cheng Wang, Qing He, Qing-Lei Zeng, Fu-Sheng Wang…
    Citation: Military Medical Research 2022 9:24
  12. LncRNA AK044604 (regulator of insulin sensitivity and autophagy, Risa) and autophagy-related factors Sirt1 and GSK3β play important roles in diabetic nephropathy (DN). In this study, we sought to explore the effe...

    Authors: Pei-Pei Su, Dong-Wei Liu, Si-Jie Zhou, Hang Chen, Xian-Ming Wu and Zhang-Suo Liu
    Citation: Military Medical Research 2022 9:23
  13. Sepsis involves life-threatening organ dysfunction and is caused by a dysregulated host response to infection. No specific therapies against sepsis have been reported. Celastrol (Cel) is a natural anti-inflamm...

    Authors: Piao Luo, Qian Zhang, Tian-Yu Zhong, Jia-Yun Chen, Jun-Zhe Zhang, Ya Tian, Liu-Hai Zheng, Fan Yang, Ling-Yun Dai, Chang Zou, Zhi-Jie Li, Jing-Hua Liu and Ji-Gang Wang
    Citation: Military Medical Research 2022 9:22
  14. Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care f...

    Authors: Qian-Qian Yuan, Shu-Xuan Xiao, Omar Farouk, Yu-Tang Du, Fereshte Sheybani, Qing Ting Tan, Sami Akbulut, Kenan Cetin, Afsaneh Alikhassi, Rami Jalal Yaghan, Irmak Durur-Subasi, Fatih Altintoprak, Tae Ik Eom, Fatih Alper, Mustafa Hasbahceci, David Martínez-Ramos…
    Citation: Military Medical Research 2022 9:20
  15. Stemness and chemoresistance contribute to cervical cancer recurrence and metastasis. In the current study, we determined the relevant players and role of N6-methyladenine (m6A) RNA methylation in cervical cancer...

    Authors: Xian Lin, Feng Wang, Jian Chen, Jing Liu, Yi-Bin Lin, Li Li, Chuan-Ben Chen and Qin Xu
    Citation: Military Medical Research 2022 9:19
  16. Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system, which can give rise to the loss of motor and sensory function. Due to its complex pathological mechanism, the treatment of...

    Authors: Yan Wang, Hong-Qian Lv, Xuan Chao, Wen-Xin Xu, Yun Liu, Gui-Xia Ling and Peng Zhang
    Citation: Military Medical Research 2022 9:16
  17. Currently, there is no formal consensus regarding a standard classification for gastric cancer (GC) patients with < 16 retrieved lymph nodes (rLNs). Here, this study aimed to validate a practical lymph node (L...

    Authors: Wei Wang, Yu-Jie Yang, Ri-Hong Zhang, Jing-Yu Deng, Zhe Sun, Sharvesh Raj Seeruttun, Zhen-Ning Wang, Hui-Mian Xu, Han Liang and Zhi-Wei Zhou
    Citation: Military Medical Research 2022 9:15
  18. Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Tran...

    Authors: Xian-Tao Zeng, Ying-Hui Jin, Tong-Zu Liu, Fang-Ming Chen, De-Gang Ding, Meng Fu, Xin-Quan Gu, Bang-Min Han, Xing Huang, Zhi Hou, Wan-Li Hu, Xin-Li Kang, Gong-Hui Li, Jian-Xing Li, Pei-Jun Li, Chao-Zhao Liang…
    Citation: Military Medical Research 2022 9:14
  19. Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogrammi...

    Authors: Shuai-Fei Ji, Lai-Xian Zhou, Zhi-Feng Sun, Jiang-Bing Xiang, Shao-Yuan Cui, Yan Li, Hua-Ting Chen, Yi-Qiong Liu, Huan-Huan Gao, Xiao-Bing Fu and Xiao-Yan Sun
    Citation: Military Medical Research 2022 9:13
  20. Studies had shown many diseases affect the stability of human microbiota, but how this relates to benign prostatic hyperplasia (BPH) has not been well understood. Hence, this study aimed to investigate the reg...

    Authors: Lu-Yao Li, Jie Han, Lan Wu, Cheng Fang, Wei-Guang Li, Jia-Min Gu, Tong Deng, Chang-Jiang Qin, Jia-Yan Nie and Xian-Tao Zeng
    Citation: Military Medical Research 2022 9:12
  21. Traditional diagnostic strategies for infectious disease detection require benchtop instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a highly miniaturized, automatic...

    Authors: Xin Wang, Xian-Zhe Hong, Yi-Wei Li, Ying Li, Jie Wang, Peng Chen and Bi-Feng Liu
    Citation: Military Medical Research 2022 9:11
  22. Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography (EI...

    Authors: Xi-Yang Ke, Wei Hou, Qi Huang, Xue Hou, Xue-Ying Bao, Wei-Xuan Kong, Cheng-Xiang Li, Yu-Qi Qiu, Si-Yi Hu and Li-Hua Dong
    Citation: Military Medical Research 2022 9:10
  23. Ultrasound-triggered microbubble destruction (UTMD) is a widely used noninvasive technology in both military and civilian medicine, which could enhance radiosensitivity of various tumors. However, little infor...

    Authors: Ying He, Xun-Hu Dong, Qiong Zhu, Ya-Li Xu, Ming-Liang Chen and Zheng Liu
    Citation: Military Medical Research 2022 9:9
  24. Early diagnosis and classification of infections increase the cure rate while decreasing complications, which is significant for severe infections, especially for war surgery. However, traditional methods rely...

    Authors: Bin-Feng Yin, Xin-Hua Wan, Ming-Zhu Yang, Chang-Cheng Qian and A. S. M. Muhtasim Fuad Sohan
    Citation: Military Medical Research 2022 9:8
  25. Airway inflammation is the core pathological process of asthma, with the key inflammatory regulators incompletely defined. Recently, fibroblast growth factor 2 (FGF2) has been reported to be an inflammatory re...

    Authors: Yuan-Yang Tan, Hui-Qin Zhou, Yu-Jing Lin, Liu-Tong Yi, Zhuang-Gui Chen, Qing-Dong Cao, Yan-Rong Guo, Zhao-Ni Wang, Shou-Deng Chen, Yang Li, De-Yun Wang, Yong-Kang Qiao and Yan Yan
    Citation: Military Medical Research 2022 9:7
  26. In sepsis, vitamin D binding protein (VDBP) has been shown to be low-expressed. The current study examined the relationship between serum VDBP level and liver injury in sepsis patients, as well as in a mouse m...

    Authors: Kun Xiao, Du-Chao Zhang, Ye Hu, Li-Cheng Song, Jian-Qiao Xu, Wan-Xue He, Pan Pan, Yu-Wei Wang and Li-Xin Xie
    Citation: Military Medical Research 2022 9:4
  27. Bacteria can evolve rapidly by acquiring new traits such as virulence, metabolic properties, and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT). Multidrug resistance in bact...

    Authors: Zhen Shen, Christoph M. Tang and Guang-Yu Liu
    Citation: Military Medical Research 2022 9:3
  28. Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. The RNA genome of SARS-CoV-2, which is highly infectious ...

    Authors: Xue-Liang Peng, Ji-Si-Yu Cheng, Hai-Lun Gong, Meng-Di Yuan, Xiao-Hong Zhao, Zibiao Li and Dai-Xu Wei
    Citation: Military Medical Research 2021 8:67
  29. The healing of bone defects can be challenging for clinicians to manage, especially after exposure to ionizing radiation. In this regard, radiation therapy and accidental exposure to gamma (γ)-ray radiation ha...

    Authors: Wei Hu, Jia-Wu Liang, Song Liao, Zhi-Dong Zhao, Yu-Xing Wang, Xiao-Fei Mao, Si-Wei Hao, Yi-Fan Wang, Heng Zhu and Bin Guo
    Citation: Military Medical Research 2021 8:61
  30. Musculoskeletal injuries (MSkIs) are a leading cause of health care utilization, as well as limited duty and disability in the US military and other armed forces. MSkIs affect members of the military during in...

    Authors: Stefan Sammito, Vedran Hadzic, Thomas Karakolis, Karen R. Kelly, Susan P. Proctor, Ainars Stepens, Graham White and Wes O. Zimmermann
    Citation: Military Medical Research 2021 8:66
  31. In the case of a terrorist attack by a “dirty bomb”, blast injuries, external irradiation and the incorporation of radioactivity are to be expected. Departing from information about the radiological attack sce...

    Authors: Alexis Rump, Stefan Eder, Cornelius Hermann, Andreas Lamkowski, Patrick Ostheim, Michael Abend and Matthias Port
    Citation: Military Medical Research 2021 8:65
  32. Triple-negative breast cancer (TNBC) is the most aggressive subtype and occurs in approximately 15–20% of diagnosed breast cancers. TNBC is characterized by its highly metastatic and recurrent features, as wel...

    Authors: Dan-Dan Zhou, Wei-Qi Bai, Xiao-Tian Zhai, Li-Ping Sun, Yong-Su Zhen, Zhuo-Rong Li and Qing-Fang Miao
    Citation: Military Medical Research 2021 8:63