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  1. Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7% of the global population and more than 500 million people worldwide. One research frontier is the development of hydro...

    Authors: Wang-Lin Duan, Li-Ning Zhang, Raghvendra Bohara, Sergio Martin-Saldaña, Fei Yang, Yi-Yang Zhao, Yong Xie, Ya-Zhong Bu and Abhay Pandit
    Citation: Military Medical Research 2023 10:4
  2. Explosions can produce blast waves, high-speed medium, thermal radiation, and chemical spatter, leading to complex and compound eye injuries. However, few studies have comprehensively investigated the clinical...

    Authors: Ying Zhang, Xin Kang, Qiong Wu, Zhong Zheng, Jun Ying and Mao-Nian Zhang
    Citation: Military Medical Research 2023 10:3
  3. Examining the health outcomes of veterans who have completed the United States Veterans Health Administration’s (VHA’s) Traumatic Brain Injury (TBI) Screening and Evaluation Program may aid in the refinement a...

    Authors: Alexandra L. Clark, Makenna B. McGill, Erin D. Ozturk, David M. Schnyer, Catherine Chanfreau-Coffinier and Victoria C. Merritt
    Citation: Military Medical Research 2023 10:2
  4. Obesity is one of the most serious global health problems, with an incidence that increases yearly and coincides with the development of cancer. Adipose tissue macrophages (ATMs) are particularly important in ...

    Authors: Bei Li, Si Sun, Juan-Juan Li, Jing-Ping Yuan, Sheng-Rong Sun and Qi Wu
    Citation: Military Medical Research 2023 10:1
  5. Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus...

    Authors: Fei Pei, Ren-Qi Yao, Chao Ren, Soheyl Bahrami, Timothy R. Billiar, Irshad H. Chaudry, De-Chang Chen, Xu-Lin Chen, Na Cui, Xiang-Ming Fang, Yan Kang, Wei-Qin Li, Wen-Xiong Li, Hua-Ping Liang, Hong-Yuan Lin, Ke-Xuan Liu…
    Citation: Military Medical Research 2022 9:74
  6. The cell cycle is at the center of cellular activities and is orchestrated by complex regulatory mechanisms, among which transcriptional regulation is one of the most important components. Alternative splicing...

    Authors: Chun-Xiao Li, Jin-Song Wang, Wen-Na Wang, Dong-Kui Xu, Yan-Tong Zhou, Fang-Zhou Sun, Yi-Qun Li, Feng-Zhu Guo, Jia-Lu Ma, Xue-Yan Zhang, Meng-Jiao Chang, Bing-He Xu, Fei Ma and Hai-Li Qian
    Citation: Military Medical Research 2022 9:71
  7. Traditional treatments for advanced hepatocellular carcinoma (HCC), such as surgical resection, transplantation, radiofrequency ablation, and chemotherapy are unsatisfactory, and therefore the exploration of p...

    Authors: Yi Lu, Yue Gao, Huan Yang, Yong Hu and Xin Li
    Citation: Military Medical Research 2022 9:69

    The Correction to this article has been published in Military Medical Research 2023 10:5

  8. The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has advanced our understanding of the pathogenesis of disease and provided valuable insights into new diagnostic and therapeutic...

    Authors: Min Su, Tao Pan, Qiu-Zhen Chen, Wei-Wei Zhou, Yi Gong, Gang Xu, Huan-Yu Yan, Si Li, Qiao-Zhen Shi, Ya Zhang, Xiao He, Chun-Jie Jiang, Shi-Cai Fan, Xia Li, Murray J. Cairns, Xi Wang…
    Citation: Military Medical Research 2022 9:68
  9. Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting a variety of cell types, whose activity and interplay must be precisely mediated for effective healing post-injury. ...

    Authors: Yuan Xiong, Bo-Bin Mi, Ze Lin, Yi-Qiang Hu, Le Yu, Kang-Kang Zha, Adriana C. Panayi, Tao Yu, Lang Chen, Zhen-Ping Liu, Anish Patel, Qian Feng, Shuan-Hu Zhou and Guo-Hui Liu
    Citation: Military Medical Research 2022 9:65
  10. Authors: Anges Yadouleton, Martin Faye, Carine Tchibozo, Mariam Oke, Oumar Faye, Thierry Lawale, Eric Denon, René Keke, Ange Dossou, Alban Zohoun, Francis Dossou, Moussa Moise Diagne, Sourakou Salifou, Khadija Leila Diatta, Mignane Ndiaye, Safietou Sankhe…
    Citation: Military Medical Research 2022 9:63
  11. Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-threatening lung diseases associated with acute and severe inflammation. Both have high mortality rates, and despite decad...

    Authors: Qian Hu, Shu Zhang, Yue Yang, Jia-Qi Yao, Wen-Fu Tang, Christopher J. Lyon, Tony Ye Hu and Mei-Hua Wan
    Citation: Military Medical Research 2022 9:61
  12. Although clozapine is an effective option for treatment-resistant schizophrenia (TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main purpose of this randomized, double-bl...

    Authors: Ming-Huan Zhu, Zhen-Jing Liu, Qiong-Yue Hu, Jia-Yu Yang, Ying Jin, Na Zhu, Ying Huang, Dian-Hong Shi, Min-Jia Liu, Hong-Yang Tan, Lei Zhao, Qin-Yu Lv, Zheng-Hui Yi, Feng-Chun Wu and Ze-Zhi Li
    Citation: Military Medical Research 2022 9:59
  13. Abnormal myocardial Nav1.5 expression and function cause lethal ventricular arrhythmias during myocardial ischemia–reperfusion (I/R). Protein inhibitor of activated STAT Y (PIASy)-mediated caveolin-3 (Cav-3) SUMO...

    Authors: Chen-Chen Hu, Xin Wei, Jin-Min Liu, Lin-Lin Han, Cheng-Kun Xia, Jing Wu, Tao You, A.-Fang Zhu, Shang-Long Yao, Shi-Ying Yuan, Hao-Dong Xu, Zheng-Yuan Xia, Ting-Ting Wang and Wei-Ke Mao
    Citation: Military Medical Research 2022 9:58
  14. Emergency front-of-neck airway (eFONA) is a life-saving procedure in “cannot intubate, cannot oxygenate” (CICO). The fastest and most reliable method of eFONA has not been determined. We compared two of the mo...

    Authors: Tomas Karlsson, Andreas Brännström, Mikael Gellerfors, Jenny Gustavsson and Mattias Günther
    Citation: Military Medical Research 2022 9:57
  15. Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is also one of the significant caus...

    Authors: Di Liu, Si-Yuan Huang, Jian-Hui Sun, Hua-Cai Zhang, Qing-Li Cai, Chu Gao, Li Li, Ju Cao, Fang Xu, Yong Zhou, Cha-Xiang Guan, Sheng-Wei Jin, Jin Deng, Xiang-Ming Fang, Jian-Xin Jiang and Ling Zeng
    Citation: Military Medical Research 2022 9:56
  16. Melatonin, a natural hormone secreted by the pineal gland, has been reported to exhibit antitumor properties through diverse mechanisms of action. However, the oncostatic function of melatonin on esophageal sq...

    Authors: Zhi-Qiang Ma, Ying-Tong Feng, Kai Guo, Dong Liu, Chang-Jian Shao, Ming-Hong Pan, Yi-Meng Zhang, Yu-Xi Zhang, Di Lu, Di Huang, Fan Zhang, Jin-Liang Wang, Bo Yang, Jing Han, Xiao-Long Yan and Yi Hu
    Citation: Military Medical Research 2022 9:54
  17. The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour immune microenvironment (TIME). This review focuses on the application of scRNA-seq in investigation of the TIME. Over ...

    Authors: Pei-Heng Li, Xiang-Yu Kong, Ya-Zhou He, Yi Liu, Xi Peng, Zhi-Hui Li, Heng Xu, Han Luo and Jihwan Park
    Citation: Military Medical Research 2022 9:52
  18. Tumor cell heterogeneity mediated drug resistance has been recognized as the stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single-cell level in a high-throughput way ...

    Authors: Biao Wang, Bang-Shun He, Xiao-Lan Ruan, Jiang Zhu, Rui Hu, Jie Wang, Ying Li, Yun-Huang Yang and Mai-Li Liu
    Citation: Military Medical Research 2022 9:51
  19. Posttraumatic stress disorder (PTSD) has been associated with volumetric and white matter microstructural changes among general and veteran populations. However, regions implicated have greatly varied and ofte...

    Authors: Madeline Romaniuk, Ying Xia, Gina Fisher, Kerstin Pannek, Jurgen Fripp, Justine Evans and Stephen Rose
    Citation: Military Medical Research 2022 9:50
  20. Data on severe and extensive burns in China are limited, as is data on the prevalence of a range of related gastrointestinal (GI) disorders [such as stress ulcers, delayed defecation, opioid-related bowel immo...

    Authors: Qiu-Lan He, Shao-Wei Gao, Ying Qin, Run-Cheng Huang, Cai-Yun Chen, Fei Zhou, Hong-Cheng Lin and Wen-Qi Huang
    Citation: Military Medical Research 2022 9:49
  21. Because of its simplicity, reliability, and replicability, the Masquelet induced membrane technique (IMT) has become one of the preferred methods for critical bone defect reconstruction in extremities. Althoug...

    Authors: Laurent Mathieu, Romain Mourtialon, Marjorie Durand, Arnaud de Rousiers, Nicolas de l’Escalopier and Jean-Marc Collombet
    Citation: Military Medical Research 2022 9:48
  22. Authors: Qian-Qian Yuan, Shu-Yuan Xiao, Omar Farouk, Yu-Tang Du, Fereshte Sheybani, Qing Ting Tan, Sami Akbulut, Kenan Cetin, Afsaneh Alikhassi, Rami Jalal Yaghan, Irmak Durur-Subasi, Fatih Altintoprak, Tae Ik Eom, Fatih Alper, Mustafa Hasbahceci, David Martínez-Ramos…
    Citation: Military Medical Research 2022 9:47

    The original article was published in Military Medical Research 2022 9:20

  23. Wear particles-induced osteolysis is a major long-term complication after total joint arthroplasty. Up to now, there is no effective treatment for wear particles-induced osteolysis except for the revision surg...

    Authors: Yang-Lin Wu, Chen-Hui Zhang, Yun Teng, Ying Pan, Nai-Cheng Liu, Pei-Xin Liu, Xu Zhu, Xin-Lin Su and Jun Lin
    Citation: Military Medical Research 2022 9:46
  24. Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors are commonly used treatments for patients with type 2 diabetes mellitus (T2DM). Both anti-diabetic treatments function by playing...

    Authors: Michael Razavi, Ying-Ying Wei, Xiao-Quan Rao and Ji-Xin Zhong
    Citation: Military Medical Research 2022 9:45
  25. Non-muscle invasive bladder cancer (NMIBC) is a major type of bladder cancer with a high incidence worldwide, resulting in a great disease burden. Treatment and surveillance are the most important part of NIMB...

    Authors: Ying-Hui Jin, Xian-Tao Zeng, Tong-Zu Liu, Zhi-Ming Bai, Zhong-Ling Dou, De-Gang Ding, Zhi-Lu Fan, Ping Han, Yi-Ran Huang, Xing Huang, Ming Li, Xiao-Dong Li, Yi-Ning Li, Xu-Hui Li, Chao-Zhao Liang, Jiu-Min Liu…
    Citation: Military Medical Research 2022 9:44
  26. Extracellular RNAs (exRNAs) are novel circulating factors that can be used as biomarkers in various diseases. Their unique and diverse kinds, as well as their role as biomarkers, make them significant biomarke...

    Authors: Abdullah Muhammad Sohail, Muhammad Babar Khawar, Ali Afzal, Ali Hassan, Sara Shahzaman and Ahmed Ali
    Citation: Military Medical Research 2022 9:43
  27. Cholangiocarcinoma (CHOL) is one of the most aggressive tumors worldwide and cannot be effectively treated by conventional and novel treatments, including immune checkpoint blockade therapy. The mRNA vaccine-b...

    Authors: Tian-Yu Tang, Xing Huang, Gang Zhang, Ming-Hao Lu and Ting-Bo Liang
    Citation: Military Medical Research 2022 9:40
  28. Autophagy dysfunction plays a crucial role in tau accumulation and neurodegeneration in Alzheimer’s disease (AD). This study aimed to investigate whether and how the accumulating tau may in turn affect autophagy.

    Authors: Meng-Zhu Li, En-Jie Liu, Qiu-Zhi Zhou, Shi-Hong Li, Shi-Jie Liu, Hai-Tao Yu, Qi-Hang Pan, Fei Sun, Ting He, Wei-Jin Wang, Dan Ke, Yu-Qi Feng, Jun Li and Jian-Zhi Wang
    Citation: Military Medical Research 2022 9:38
  29. Traumatic colon injury (TCI) is a common disease during wartime. Prolongation of posttraumatic survival time is an effective approach to patient outcome improvement. However, there is a lack of basic research ...

    Authors: Bo Cao, Rui-Yang Zhao, Hang-Hang Li, Xing-Ming Xu, Hao Cui, Huan Deng, Lin Chen and Bo Wei
    Citation: Military Medical Research 2022 9:37
  30. The literature is full of claims regarding the consumption of polyphenol or polyamine-rich foods that offer some protection from developing cardiovascular disease (CVD). This is achieved by preventing cardiac ...

    Authors: Lei Pang, Xi Jiang, Xin Lian, Jie Chen, Er-Fei Song, Lei-Gang Jin, Zheng-Yuan Xia, Hai-Chun Ma and Yin Cai
    Citation: Military Medical Research 2022 9:33
  31. Due to the outbreak and rapid spread of coronavirus disease 2019 (COVID-19), more than 160 million patients have become convalescents worldwide to date. Significant alterations have occurred in the gut and ora...

    Authors: Guang-Ying Cui, Ben-Chen Rao, Zhao-Hai Zeng, Xue-Mei Wang, Tong Ren, Hai-Yu Wang, Hong Luo, Hong-Yan Ren, Chao Liu, Su-Ying Ding, Jun-Jie Tan, Zhen-Guo Liu, Ya-Wen Zou, Zhi-Gang Ren and Zu-Jiang Yu
    Citation: Military Medical Research 2022 9:32
  32. Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indi...

    Authors: Peng Gao, Yan-Qing Liu, Wei Xiao, Fei Xia, Jia-Yun Chen, Li-Wei Gu, Fan Yang, Liu-Hai Zheng, Jun-Zhe Zhang, Qian Zhang, Zhi-Jie Li, Yu-Qing Meng, Yong-Ping Zhu, Huan Tang, Qiao-Li Shi, Qiu-Yan Guo…
    Citation: Military Medical Research 2022 9:30