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  1. Choosing the appropriate antipsychotic drug (APD) treatment for patients with schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly variable and difficult to predict due to the lac...

    Authors: Liang-Kun Guo, Yi Su, Yu-Ya-Nan Zhang, Hao Yu, Zhe Lu, Wen-Qiang Li, Yong-Feng Yang, Xiao Xiao, Hao Yan, Tian-Lan Lu, Jun Li, Yun-Dan Liao, Zhe-Wei Kang, Li-Fang Wang, Yue Li, Ming Li…
    Citation: Military Medical Research 2023 10:24
  2. Continuous renal replacement therapy (CRRT) is widely used for treating critically-ill patients in the emergency department in China. Anticoagulant therapy is needed to prevent clotting in the extracorporeal c...

    Authors: Shu-Yuan Liu, Sheng-Yong Xu, Lu Yin, Ting Yang, Kui Jin, Qiu-Bin Zhang, Feng Sun, Ding-Yu Tan, Tian-Yu Xin, Yu-Guo Chen, Xiao-Dong Zhao, Xue-Zhong Yu and Jun Xu
    Citation: Military Medical Research 2023 10:23
  3. Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’ anatomy. However, the interpretation of medical images can be highly subjective and dependent on the ex...

    Authors: Yuan-Peng Zhang, Xin-Yun Zhang, Yu-Ting Cheng, Bing Li, Xin-Zhi Teng, Jiang Zhang, Saikit Lam, Ta Zhou, Zong-Rui Ma, Jia-Bao Sheng, Victor C. W. Tam, Shara W. Y. Lee, Hong Ge and Jing Cai
    Citation: Military Medical Research 2023 10:22
  4. Treatment of methicillin-resistant Staphylococcus aureus (MRSA) biofilm infections in implant placement surgery is limited by the lack of antimicrobial activity of titanium (Ti) implants. There is a need to explo...

    Authors: Yong-Lin Yu, Jun-Jie Wu, Chuan-Chuan Lin, Xian Qin, Franklin R. Tay, Li Miao, Bai-Long Tao and Yang Jiao
    Citation: Military Medical Research 2023 10:21
  5. A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes, such as natural cell membranes or subcellular structure-derived membranes. This strategy endows cloaked nano...

    Authors: Daniela Lopes, Joana Lopes, Miguel Pereira-Silva, Diana Peixoto, Navid Rabiee, Francisco Veiga, Omid Moradi, Zhan-Hu Guo, Xiang-Dong Wang, João Conde, Pooyan Makvandi and Ana Cláudia Paiva-Santos
    Citation: Military Medical Research 2023 10:19
  6. Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or synthetic materials, biomimetic s...

    Authors: Shuai Liu, Jiang-Ming Yu, Yan-Chang Gan, Xiao-Zhong Qiu, Zhe-Chen Gao, Huan Wang, Shi-Xuan Chen, Yuan Xiong, Guo-Hui Liu, Si-En Lin, Alec McCarthy, Johnson V. John, Dai-Xu Wei and Hong-Hao Hou
    Citation: Military Medical Research 2023 10:16
  7. Reconstruction of damaged tissues requires both surface hemostasis and tissue bridging. Tissues with damage resulting from physical trauma or surgical treatments may have arbitrary surface topographies, making...

    Authors: Yao-Ting Xue, Ming-Yu Chen, Jia-Sheng Cao, Lei Wang, Jia-Hao Hu, Si-Yang Li, Ji-Liang Shen, Xin-Ge Li, Kai-Hang Zhang, Shu-Qiang Hao, Sarun Juengpanich, Si-Bo Cheng, Tuck-Whye Wong, Xu-Xu Yang, Tie-Feng Li, Xiu-Jun Cai…
    Citation: Military Medical Research 2023 10:15
  8. Vascular hyporeactivity and leakage are key pathophysiologic features that produce multi-organ damage upon sepsis. We hypothesized that pericytes, a group of pluripotent cells that maintain vascular integrity ...

    Authors: Zi-Sen Zhang, Yi-Yan Liu, Shuang-Shuang He, Dai-Qin Bao, Hong-Chen Wang, Jie Zhang, Xiao-Yong Peng, Jia-Tao Zang, Yu Zhu, Yue Wu, Qing-Hui Li, Tao Li and Liang-Ming Liu
    Citation: Military Medical Research 2023 10:13
  9. The rapid development of genome editing technology has brought major breakthroughs in the fields of life science and medicine. In recent years, the clustered regularly interspaced short palindromic repeats (CR...

    Authors: Zhen-Hua Li, Jun Wang, Jing-Ping Xu, Jian Wang and Xiao Yang
    Citation: Military Medical Research 2023 10:12
  10. Gulf War Illness (GWI) encompass a spectrum of maladies specific to troops deployed during the Persian Gulf War (1990–1991). There are several hypothesized factors believed to contribute to GWI, including (but...

    Authors: Rami Elhaj and Joseph M. Reynolds
    Citation: Military Medical Research 2023 10:11
  11. Drug discovery is a crucial part of human healthcare and has dramatically benefited human lifespan and life quality in recent centuries, however, it is usually time- and effort-consuming. Structural biology ha...

    Authors: Kong-Fu Zhu, Chuang Yuan, Yong-Ming Du, Kai-Lei Sun, Xiao-Kang Zhang, Horst Vogel, Xu-Dong Jia, Yuan-Zhu Gao, Qin-Fen Zhang, Da-Ping Wang and Hua-Wei Zhang
    Citation: Military Medical Research 2023 10:10
  12. Gene therapy has shown great potential to treat various diseases by repairing the abnormal gene function. However, a great challenge in bringing the nucleic acid formulations to the market is the safe and effe...

    Authors: Yu-Qi Zhang, Ran-Ran Guo, Yong-Hu Chen, Tian-Cheng Li, Wen-Zhen Du, Rong-Wu Xiang, Ji-Bin Guan, Yu-Peng Li, Yuan-Yu Huang, Zhi-Qiang Yu, Yin Cai, Peng Zhang and Gui-Xia Ling
    Citation: Military Medical Research 2023 10:9
  13. Fungi and bacteria afflict humans with innumerous pathogen-related infections and ailments. Most of the commonly employed microbicidal agents target commensal and pathogenic microorganisms without discriminati...

    Authors: Pooyan Makvandi, Hao Song, Cynthia K. Y. Yiu, Rossella Sartorius, Ehsan Nazarzadeh Zare, Navid Rabiee, Wei-Xi Wu, Ana Cláudia Paiva-Santos, Xiang-Dong Wang, Cheng-Zhong Yu and Franklin R. Tay
    Citation: Military Medical Research 2023 10:8
  14. Triclosan [5-chloro-2-(2,4-dichlorophenoxy) phenol, TCS], a common antimicrobial additive in many personal care and health care products, is frequently detected in human blood and urine. Therefore, it has been...

    Authors: Yun-Meng Bai, Fan Yang, Piao Luo, Lu-Lin Xie, Jun-Hui Chen, Yu-Dong Guan, Hong-Chao Zhou, Teng-Fei Xu, Hui-Wen Hao, Bing Chen, Jia-Hui Zhao, Cai-Ling Liang, Ling-Yun Dai, Qing-Shan Geng and Ji-Gang Wang
    Citation: Military Medical Research 2023 10:7
  15. Artificial intelligence (AI), a branch of machine learning (ML) has been increasingly employed in the research of trauma in various aspects. Hemorrhage is the most common cause of trauma-related death. To bett...

    Authors: Henry T. Peng, M. Musaab Siddiqui, Shawn G. Rhind, Jing Zhang, Luis Teodoro da Luz and Andrew Beckett
    Citation: Military Medical Research 2023 10:6
  16. Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7% of the global population and more than 500 million people worldwide. One research frontier is the development of hydro...

    Authors: Wang-Lin Duan, Li-Ning Zhang, Raghvendra Bohara, Sergio Martin-Saldaña, Fei Yang, Yi-Yang Zhao, Yong Xie, Ya-Zhong Bu and Abhay Pandit
    Citation: Military Medical Research 2023 10:4
  17. Explosions can produce blast waves, high-speed medium, thermal radiation, and chemical spatter, leading to complex and compound eye injuries. However, few studies have comprehensively investigated the clinical...

    Authors: Ying Zhang, Xin Kang, Qiong Wu, Zhong Zheng, Jun Ying and Mao-Nian Zhang
    Citation: Military Medical Research 2023 10:3
  18. Examining the health outcomes of veterans who have completed the United States Veterans Health Administration’s (VHA’s) Traumatic Brain Injury (TBI) Screening and Evaluation Program may aid in the refinement a...

    Authors: Alexandra L. Clark, Makenna B. McGill, Erin D. Ozturk, David M. Schnyer, Catherine Chanfreau-Coffinier and Victoria C. Merritt
    Citation: Military Medical Research 2023 10:2
  19. Obesity is one of the most serious global health problems, with an incidence that increases yearly and coincides with the development of cancer. Adipose tissue macrophages (ATMs) are particularly important in ...

    Authors: Bei Li, Si Sun, Juan-Juan Li, Jing-Ping Yuan, Sheng-Rong Sun and Qi Wu
    Citation: Military Medical Research 2023 10:1
  20. Emerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus...

    Authors: Fei Pei, Ren-Qi Yao, Chao Ren, Soheyl Bahrami, Timothy R. Billiar, Irshad H. Chaudry, De-Chang Chen, Xu-Lin Chen, Na Cui, Xiang-Ming Fang, Yan Kang, Wei-Qin Li, Wen-Xiong Li, Hua-Ping Liang, Hong-Yuan Lin, Ke-Xuan Liu…
    Citation: Military Medical Research 2022 9:74
  21. The cell cycle is at the center of cellular activities and is orchestrated by complex regulatory mechanisms, among which transcriptional regulation is one of the most important components. Alternative splicing...

    Authors: Chun-Xiao Li, Jin-Song Wang, Wen-Na Wang, Dong-Kui Xu, Yan-Tong Zhou, Fang-Zhou Sun, Yi-Qun Li, Feng-Zhu Guo, Jia-Lu Ma, Xue-Yan Zhang, Meng-Jiao Chang, Bing-He Xu, Fei Ma and Hai-Li Qian
    Citation: Military Medical Research 2022 9:71
  22. Traditional treatments for advanced hepatocellular carcinoma (HCC), such as surgical resection, transplantation, radiofrequency ablation, and chemotherapy are unsatisfactory, and therefore the exploration of p...

    Authors: Yi Lu, Yue Gao, Huan Yang, Yong Hu and Xin Li
    Citation: Military Medical Research 2022 9:69

    The Correction to this article has been published in Military Medical Research 2023 10:5

  23. The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has advanced our understanding of the pathogenesis of disease and provided valuable insights into new diagnostic and therapeutic...

    Authors: Min Su, Tao Pan, Qiu-Zhen Chen, Wei-Wei Zhou, Yi Gong, Gang Xu, Huan-Yu Yan, Si Li, Qiao-Zhen Shi, Ya Zhang, Xiao He, Chun-Jie Jiang, Shi-Cai Fan, Xia Li, Murray J. Cairns, Xi Wang…
    Citation: Military Medical Research 2022 9:68
  24. Bone, cartilage, and soft tissue regeneration is a complex spatiotemporal process recruiting a variety of cell types, whose activity and interplay must be precisely mediated for effective healing post-injury. ...

    Authors: Yuan Xiong, Bo-Bin Mi, Ze Lin, Yi-Qiang Hu, Le Yu, Kang-Kang Zha, Adriana C. Panayi, Tao Yu, Lang Chen, Zhen-Ping Liu, Anish Patel, Qian Feng, Shuan-Hu Zhou and Guo-Hui Liu
    Citation: Military Medical Research 2022 9:65
  25. Authors: Anges Yadouleton, Martin Faye, Carine Tchibozo, Mariam Oke, Oumar Faye, Thierry Lawale, Eric Denon, René Keke, Ange Dossou, Alban Zohoun, Francis Dossou, Moussa Moise Diagne, Sourakou Salifou, Khadija Leila Diatta, Mignane Ndiaye, Safietou Sankhe…
    Citation: Military Medical Research 2022 9:63
  26. Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common life-threatening lung diseases associated with acute and severe inflammation. Both have high mortality rates, and despite decad...

    Authors: Qian Hu, Shu Zhang, Yue Yang, Jia-Qi Yao, Wen-Fu Tang, Christopher J. Lyon, Tony Ye Hu and Mei-Hua Wan
    Citation: Military Medical Research 2022 9:61
  27. Although clozapine is an effective option for treatment-resistant schizophrenia (TRS), there are still 1/3 to 1/2 of TRS patients who do not respond to clozapine. The main purpose of this randomized, double-bl...

    Authors: Ming-Huan Zhu, Zhen-Jing Liu, Qiong-Yue Hu, Jia-Yu Yang, Ying Jin, Na Zhu, Ying Huang, Dian-Hong Shi, Min-Jia Liu, Hong-Yang Tan, Lei Zhao, Qin-Yu Lv, Zheng-Hui Yi, Feng-Chun Wu and Ze-Zhi Li
    Citation: Military Medical Research 2022 9:59
  28. Abnormal myocardial Nav1.5 expression and function cause lethal ventricular arrhythmias during myocardial ischemia–reperfusion (I/R). Protein inhibitor of activated STAT Y (PIASy)-mediated caveolin-3 (Cav-3) SUMO...

    Authors: Chen-Chen Hu, Xin Wei, Jin-Min Liu, Lin-Lin Han, Cheng-Kun Xia, Jing Wu, Tao You, A.-Fang Zhu, Shang-Long Yao, Shi-Ying Yuan, Hao-Dong Xu, Zheng-Yuan Xia, Ting-Ting Wang and Wei-Ke Mao
    Citation: Military Medical Research 2022 9:58
  29. Emergency front-of-neck airway (eFONA) is a life-saving procedure in “cannot intubate, cannot oxygenate” (CICO). The fastest and most reliable method of eFONA has not been determined. We compared two of the mo...

    Authors: Tomas Karlsson, Andreas Brännström, Mikael Gellerfors, Jenny Gustavsson and Mattias Günther
    Citation: Military Medical Research 2022 9:57
  30. Sepsis is a common complication of combat injuries and trauma, and is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. It is also one of the significant caus...

    Authors: Di Liu, Si-Yuan Huang, Jian-Hui Sun, Hua-Cai Zhang, Qing-Li Cai, Chu Gao, Li Li, Ju Cao, Fang Xu, Yong Zhou, Cha-Xiang Guan, Sheng-Wei Jin, Jin Deng, Xiang-Ming Fang, Jian-Xin Jiang and Ling Zeng
    Citation: Military Medical Research 2022 9:56
  31. Melatonin, a natural hormone secreted by the pineal gland, has been reported to exhibit antitumor properties through diverse mechanisms of action. However, the oncostatic function of melatonin on esophageal sq...

    Authors: Zhi-Qiang Ma, Ying-Tong Feng, Kai Guo, Dong Liu, Chang-Jian Shao, Ming-Hong Pan, Yi-Meng Zhang, Yu-Xi Zhang, Di Lu, Di Huang, Fan Zhang, Jin-Liang Wang, Bo Yang, Jing Han, Xiao-Long Yan and Yi Hu
    Citation: Military Medical Research 2022 9:54
  32. The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour immune microenvironment (TIME). This review focuses on the application of scRNA-seq in investigation of the TIME. Over ...

    Authors: Pei-Heng Li, Xiang-Yu Kong, Ya-Zhou He, Yi Liu, Xi Peng, Zhi-Hui Li, Heng Xu, Han Luo and Jihwan Park
    Citation: Military Medical Research 2022 9:52
  33. Tumor cell heterogeneity mediated drug resistance has been recognized as the stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single-cell level in a high-throughput way ...

    Authors: Biao Wang, Bang-Shun He, Xiao-Lan Ruan, Jiang Zhu, Rui Hu, Jie Wang, Ying Li, Yun-Huang Yang and Mai-Li Liu
    Citation: Military Medical Research 2022 9:51
  34. Posttraumatic stress disorder (PTSD) has been associated with volumetric and white matter microstructural changes among general and veteran populations. However, regions implicated have greatly varied and ofte...

    Authors: Madeline Romaniuk, Ying Xia, Gina Fisher, Kerstin Pannek, Jurgen Fripp, Justine Evans and Stephen Rose
    Citation: Military Medical Research 2022 9:50
  35. Data on severe and extensive burns in China are limited, as is data on the prevalence of a range of related gastrointestinal (GI) disorders [such as stress ulcers, delayed defecation, opioid-related bowel immo...

    Authors: Qiu-Lan He, Shao-Wei Gao, Ying Qin, Run-Cheng Huang, Cai-Yun Chen, Fei Zhou, Hong-Cheng Lin and Wen-Qi Huang
    Citation: Military Medical Research 2022 9:49