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  1. Melatonin, a natural hormone secreted by the pineal gland, has been reported to exhibit antitumor properties through diverse mechanisms of action. However, the oncostatic function of melatonin on esophageal sq...

    Authors: Zhi-Qiang Ma, Ying-Tong Feng, Kai Guo, Dong Liu, Chang-Jian Shao, Ming-Hong Pan, Yi-Meng Zhang, Yu-Xi Zhang, Di Lu, Di Huang, Fan Zhang, Jin-Liang Wang, Bo Yang, Jing Han, Xiao-Long Yan and Yi Hu
    Citation: Military Medical Research 2022 9:54
  2. The advent of single-cell RNA sequencing (scRNA-seq) has provided insight into the tumour immune microenvironment (TIME). This review focuses on the application of scRNA-seq in investigation of the TIME. Over ...

    Authors: Pei-Heng Li, Xiang-Yu Kong, Ya-Zhou He, Yi Liu, Xi Peng, Zhi-Hui Li, Heng Xu, Han Luo and Jihwan Park
    Citation: Military Medical Research 2022 9:52
  3. Tumor cell heterogeneity mediated drug resistance has been recognized as the stumbling block of cancer treatment. Elucidating the cytotoxicity of anticancer drugs at single-cell level in a high-throughput way ...

    Authors: Biao Wang, Bang-Shun He, Xiao-Lan Ruan, Jiang Zhu, Rui Hu, Jie Wang, Ying Li, Yun-Huang Yang and Mai-Li Liu
    Citation: Military Medical Research 2022 9:51
  4. Posttraumatic stress disorder (PTSD) has been associated with volumetric and white matter microstructural changes among general and veteran populations. However, regions implicated have greatly varied and ofte...

    Authors: Madeline Romaniuk, Ying Xia, Gina Fisher, Kerstin Pannek, Jurgen Fripp, Justine Evans and Stephen Rose
    Citation: Military Medical Research 2022 9:50
  5. Data on severe and extensive burns in China are limited, as is data on the prevalence of a range of related gastrointestinal (GI) disorders [such as stress ulcers, delayed defecation, opioid-related bowel immo...

    Authors: Qiu-Lan He, Shao-Wei Gao, Ying Qin, Run-Cheng Huang, Cai-Yun Chen, Fei Zhou, Hong-Cheng Lin and Wen-Qi Huang
    Citation: Military Medical Research 2022 9:49
  6. Because of its simplicity, reliability, and replicability, the Masquelet induced membrane technique (IMT) has become one of the preferred methods for critical bone defect reconstruction in extremities. Althoug...

    Authors: Laurent Mathieu, Romain Mourtialon, Marjorie Durand, Arnaud de Rousiers, Nicolas de l’Escalopier and Jean-Marc Collombet
    Citation: Military Medical Research 2022 9:48
  7. Authors: Qian-Qian Yuan, Shu-Yuan Xiao, Omar Farouk, Yu-Tang Du, Fereshte Sheybani, Qing Ting Tan, Sami Akbulut, Kenan Cetin, Afsaneh Alikhassi, Rami Jalal Yaghan, Irmak Durur-Subasi, Fatih Altintoprak, Tae Ik Eom, Fatih Alper, Mustafa Hasbahceci, David Martínez-Ramos…
    Citation: Military Medical Research 2022 9:47

    The original article was published in Military Medical Research 2022 9:20

  8. Wear particles-induced osteolysis is a major long-term complication after total joint arthroplasty. Up to now, there is no effective treatment for wear particles-induced osteolysis except for the revision surg...

    Authors: Yang-Lin Wu, Chen-Hui Zhang, Yun Teng, Ying Pan, Nai-Cheng Liu, Pei-Xin Liu, Xu Zhu, Xin-Lin Su and Jun Lin
    Citation: Military Medical Research 2022 9:46
  9. Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors are commonly used treatments for patients with type 2 diabetes mellitus (T2DM). Both anti-diabetic treatments function by playing...

    Authors: Michael Razavi, Ying-Ying Wei, Xiao-Quan Rao and Ji-Xin Zhong
    Citation: Military Medical Research 2022 9:45
  10. Non-muscle invasive bladder cancer (NMIBC) is a major type of bladder cancer with a high incidence worldwide, resulting in a great disease burden. Treatment and surveillance are the most important part of NIMB...

    Authors: Ying-Hui Jin, Xian-Tao Zeng, Tong-Zu Liu, Zhi-Ming Bai, Zhong-Ling Dou, De-Gang Ding, Zhi-Lu Fan, Ping Han, Yi-Ran Huang, Xing Huang, Ming Li, Xiao-Dong Li, Yi-Ning Li, Xu-Hui Li, Chao-Zhao Liang, Jiu-Min Liu…
    Citation: Military Medical Research 2022 9:44
  11. Extracellular RNAs (exRNAs) are novel circulating factors that can be used as biomarkers in various diseases. Their unique and diverse kinds, as well as their role as biomarkers, make them significant biomarke...

    Authors: Abdullah Muhammad Sohail, Muhammad Babar Khawar, Ali Afzal, Ali Hassan, Sara Shahzaman and Ahmed Ali
    Citation: Military Medical Research 2022 9:43
  12. Cholangiocarcinoma (CHOL) is one of the most aggressive tumors worldwide and cannot be effectively treated by conventional and novel treatments, including immune checkpoint blockade therapy. The mRNA vaccine-b...

    Authors: Tian-Yu Tang, Xing Huang, Gang Zhang, Ming-Hao Lu and Ting-Bo Liang
    Citation: Military Medical Research 2022 9:40
  13. Autophagy dysfunction plays a crucial role in tau accumulation and neurodegeneration in Alzheimer’s disease (AD). This study aimed to investigate whether and how the accumulating tau may in turn affect autophagy.

    Authors: Meng-Zhu Li, En-Jie Liu, Qiu-Zhi Zhou, Shi-Hong Li, Shi-Jie Liu, Hai-Tao Yu, Qi-Hang Pan, Fei Sun, Ting He, Wei-Jin Wang, Dan Ke, Yu-Qi Feng, Jun Li and Jian-Zhi Wang
    Citation: Military Medical Research 2022 9:38
  14. Traumatic colon injury (TCI) is a common disease during wartime. Prolongation of posttraumatic survival time is an effective approach to patient outcome improvement. However, there is a lack of basic research ...

    Authors: Bo Cao, Rui-Yang Zhao, Hang-Hang Li, Xing-Ming Xu, Hao Cui, Huan Deng, Lin Chen and Bo Wei
    Citation: Military Medical Research 2022 9:37
  15. The literature is full of claims regarding the consumption of polyphenol or polyamine-rich foods that offer some protection from developing cardiovascular disease (CVD). This is achieved by preventing cardiac ...

    Authors: Lei Pang, Xi Jiang, Xin Lian, Jie Chen, Er-Fei Song, Lei-Gang Jin, Zheng-Yuan Xia, Hai-Chun Ma and Yin Cai
    Citation: Military Medical Research 2022 9:33
  16. Due to the outbreak and rapid spread of coronavirus disease 2019 (COVID-19), more than 160 million patients have become convalescents worldwide to date. Significant alterations have occurred in the gut and ora...

    Authors: Guang-Ying Cui, Ben-Chen Rao, Zhao-Hai Zeng, Xue-Mei Wang, Tong Ren, Hai-Yu Wang, Hong Luo, Hong-Yan Ren, Chao Liu, Su-Ying Ding, Jun-Jie Tan, Zhen-Guo Liu, Ya-Wen Zou, Zhi-Gang Ren and Zu-Jiang Yu
    Citation: Military Medical Research 2022 9:32
  17. Malaria is a devastating infectious disease that disproportionally threatens hundreds of millions of people in developing countries. In the history of anti-malaria campaign, chloroquine (CQ) has played an indi...

    Authors: Peng Gao, Yan-Qing Liu, Wei Xiao, Fei Xia, Jia-Yun Chen, Li-Wei Gu, Fan Yang, Liu-Hai Zheng, Jun-Zhe Zhang, Qian Zhang, Zhi-Jie Li, Yu-Qing Meng, Yong-Ping Zhu, Huan Tang, Qiao-Li Shi, Qiu-Yan Guo…
    Citation: Military Medical Research 2022 9:30
  18. Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor, and it is associated with poor prognosis. Its characteristics of being highly invasive and undergoing heterogeneous genetic mutat...

    Authors: Qing-Long Guo, Xing-Liang Dai, Meng-Yuan Yin, Hong-Wei Cheng, Hai-Sheng Qian, Hua Wang, Dao-Ming Zhu and Xian-Wen Wang
    Citation: Military Medical Research 2022 9:26
  19. Cerebral ischemia-reperfusion injury (CIRI) refers to a secondary brain injury that can occur when the blood supply to the ischemic brain tissue is restored. However, the mechanism underlying such injury remai...

    Authors: Xue Zeng, Yun-Dong Zhang, Rui-Yan Ma, Yuan-Jing Chen, Xin-Ming Xiang, Dong-Yao Hou, Xue-Han Li, He Huang, Tao Li and Chen-Yang Duan
    Citation: Military Medical Research 2022 9:25
  20. Mucosal-associated invariant T (MAIT) cells are systemically depleted in human immunodeficiency virus type 1 (HIV-1) infected patients and are not replenished even after successful combined antiretroviral ther...

    Authors: Peng Xia, Xu-Dong Xing, Cui-Xian Yang, Xue-Jiao Liao, Fu-Hua Liu, Hui-Huang Huang, Chao Zhang, Jin-Wen Song, Yan-Mei Jiao, Ming Shi, Tian-Jun Jiang, Chun-Bao Zhou, Xi-Cheng Wang, Qing He, Qing-Lei Zeng, Fu-Sheng Wang…
    Citation: Military Medical Research 2022 9:24
  21. LncRNA AK044604 (regulator of insulin sensitivity and autophagy, Risa) and autophagy-related factors Sirt1 and GSK3β play important roles in diabetic nephropathy (DN). In this study, we sought to explore the effe...

    Authors: Pei-Pei Su, Dong-Wei Liu, Si-Jie Zhou, Hang Chen, Xian-Ming Wu and Zhang-Suo Liu
    Citation: Military Medical Research 2022 9:23
  22. Sepsis involves life-threatening organ dysfunction and is caused by a dysregulated host response to infection. No specific therapies against sepsis have been reported. Celastrol (Cel) is a natural anti-inflamm...

    Authors: Piao Luo, Qian Zhang, Tian-Yu Zhong, Jia-Yun Chen, Jun-Zhe Zhang, Ya Tian, Liu-Hai Zheng, Fan Yang, Ling-Yun Dai, Chang Zou, Zhi-Jie Li, Jing-Hua Liu and Ji-Gang Wang
    Citation: Military Medical Research 2022 9:22
  23. Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care f...

    Authors: Qian-Qian Yuan, Shu-Yuan Xiao, Omar Farouk, Yu-Tang Du, Fereshte Sheybani, Qing Ting Tan, Sami Akbulut, Kenan Cetin, Afsaneh Alikhassi, Rami Jalal Yaghan, Irmak Durur-Subasi, Fatih Altintoprak, Tae Ik Eom, Fatih Alper, Mustafa Hasbahceci, David Martínez-Ramos…
    Citation: Military Medical Research 2022 9:20

    The Correction to this article has been published in Military Medical Research 2022 9:47

  24. Stemness and chemoresistance contribute to cervical cancer recurrence and metastasis. In the current study, we determined the relevant players and role of N6-methyladenine (m6A) RNA methylation in cervical cancer...

    Authors: Xian Lin, Feng Wang, Jian Chen, Jing Liu, Yi-Bin Lin, Li Li, Chuan-Ben Chen and Qin Xu
    Citation: Military Medical Research 2022 9:19
  25. Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system, which can give rise to the loss of motor and sensory function. Due to its complex pathological mechanism, the treatment of...

    Authors: Yan Wang, Hong-Qian Lv, Xuan Chao, Wen-Xin Xu, Yun Liu, Gui-Xia Ling and Peng Zhang
    Citation: Military Medical Research 2022 9:16
  26. Currently, there is no formal consensus regarding a standard classification for gastric cancer (GC) patients with < 16 retrieved lymph nodes (rLNs). Here, this study aimed to validate a practical lymph node (L...

    Authors: Wei Wang, Yu-Jie Yang, Ri-Hong Zhang, Jing-Yu Deng, Zhe Sun, Sharvesh Raj Seeruttun, Zhen-Ning Wang, Hui-Mian Xu, Han Liang and Zhi-Wei Zhou
    Citation: Military Medical Research 2022 9:15
  27. Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Tran...

    Authors: Xian-Tao Zeng, Ying-Hui Jin, Tong-Zu Liu, Fang-Ming Chen, De-Gang Ding, Meng Fu, Xin-Quan Gu, Bang-Min Han, Xing Huang, Zhi Hou, Wan-Li Hu, Xin-Li Kang, Gong-Hui Li, Jian-Xing Li, Pei-Jun Li, Chao-Zhao Liang…
    Citation: Military Medical Research 2022 9:14
  28. Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogrammi...

    Authors: Shuai-Fei Ji, Lai-Xian Zhou, Zhi-Feng Sun, Jiang-Bing Xiang, Shao-Yuan Cui, Yan Li, Hua-Ting Chen, Yi-Qiong Liu, Huan-Huan Gao, Xiao-Bing Fu and Xiao-Yan Sun
    Citation: Military Medical Research 2022 9:13
  29. Studies had shown many diseases affect the stability of human microbiota, but how this relates to benign prostatic hyperplasia (BPH) has not been well understood. Hence, this study aimed to investigate the reg...

    Authors: Lu-Yao Li, Jie Han, Lan Wu, Cheng Fang, Wei-Guang Li, Jia-Min Gu, Tong Deng, Chang-Jiang Qin, Jia-Yan Nie and Xian-Tao Zeng
    Citation: Military Medical Research 2022 9:12
  30. Traditional diagnostic strategies for infectious disease detection require benchtop instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a highly miniaturized, automatic...

    Authors: Xin Wang, Xian-Zhe Hong, Yi-Wei Li, Ying Li, Jie Wang, Peng Chen and Bi-Feng Liu
    Citation: Military Medical Research 2022 9:11
  31. Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography (EI...

    Authors: Xi-Yang Ke, Wei Hou, Qi Huang, Xue Hou, Xue-Ying Bao, Wei-Xuan Kong, Cheng-Xiang Li, Yu-Qi Qiu, Si-Yi Hu and Li-Hua Dong
    Citation: Military Medical Research 2022 9:10
  32. Ultrasound-triggered microbubble destruction (UTMD) is a widely used noninvasive technology in both military and civilian medicine, which could enhance radiosensitivity of various tumors. However, little infor...

    Authors: Ying He, Xun-Hu Dong, Qiong Zhu, Ya-Li Xu, Ming-Liang Chen and Zheng Liu
    Citation: Military Medical Research 2022 9:9
  33. Early diagnosis and classification of infections increase the cure rate while decreasing complications, which is significant for severe infections, especially for war surgery. However, traditional methods rely...

    Authors: Bin-Feng Yin, Xin-Hua Wan, Ming-Zhu Yang, Chang-Cheng Qian and A. S. M. Muhtasim Fuad Sohan
    Citation: Military Medical Research 2022 9:8
  34. Airway inflammation is the core pathological process of asthma, with the key inflammatory regulators incompletely defined. Recently, fibroblast growth factor 2 (FGF2) has been reported to be an inflammatory re...

    Authors: Yuan-Yang Tan, Hui-Qin Zhou, Yu-Jing Lin, Liu-Tong Yi, Zhuang-Gui Chen, Qing-Dong Cao, Yan-Rong Guo, Zhao-Ni Wang, Shou-Deng Chen, Yang Li, De-Yun Wang, Yong-Kang Qiao and Yan Yan
    Citation: Military Medical Research 2022 9:7