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  2. G-protein coupled receptors (GPCRs) are recognized as attractive targets for drug therapy. However, it remains poorly understood how GPCRs, except for a few chemokine receptors, regulate the progression of liv...

    Authors: Kun Zhang, Meng-Xia Zhang, Xiao-Xiang Meng, Jing Zhu, Jia-Jun Wang, Yi-Fan He, Ye-Hua Li, Si-Cong Zhao, Zhe-Min Shi, Li-Na Zheng, Tao Han and Wei Hong
    Citation: Military Medical Research 2023 10:56
    Content type: Research Published on:

  4. Degenerative musculoskeletal diseases are structural and functional failures of the musculoskeletal system, including osteoarthritis, osteoporosis, intervertebral disc degeneration (IVDD), and sarcopenia. As t...

    Authors: Ze-Qin Wen, Jun Lin, Wen-Qing Xie, Yun-Han Shan, Ge-Hua Zhen and Yu-Sheng Li
    Citation: Military Medical Research 2023 10:54
    Content type: Review Published on:

  5. Nonalcoholic fatty liver disease (NAFLD) is associated with disordered lipid and iron metabolism. Our previous study has substantiated the pivotal role of Caveolin-1 (Cav-1) in protecting hepatocytes and media...

    Authors: Guang-Hui Deng, Chao-Feng Wu, Yun-Jia Li, Hao Shi, Wei-Chao Zhong, Mu-Keng Hong, Jun-Jie Li, Jia-Min Zhao, Chang Liu, Meng-Chen Qin, Zhi-Yun Zeng, Wei-Min Zhang, Ken Kin Lam Yung, Zhi-Ping Lv and Lei Gao
    Citation: Military Medical Research 2023 10:53
    Content type: Research Published on:

  7. Regulation of gut microbiota and its impact on human health is the theme of intensive research. The incidence and prevalence of atrial fibrillation (AF) are continuously escalating as the global population age...

    Authors: Na Li, Ling Wang, Lei Li, Meng-Zhao Yang, Qing-Xiang Wang, Xi-Wen Bai, Feng Gao, Yi-Qiang Yuan, Zu-Jiang Yu and Zhi-Gang Ren
    Citation: Military Medical Research 2023 10:51
    Content type: Review Published on:

  8. In the United States (US), the Surveillance, Epidemiology, and End Results (SEER) program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis...

    Authors: Wen-Qiang Che, Yuan-Jie Li, Chi-Kwan Tsang, Yu-Jiao Wang, Zheng Chen, Xiang-Yu Wang, An-Ding Xu and Jun Lyu
    Citation: Military Medical Research 2023 10:50
    Content type: Review Published on:

  9. As the body’s integumentary system, the skin is vulnerable to injuries. The subsequent wound healing processes aim to restore dermal and epidermal integrity and functionality. To this end, multiple tissue-resi...

    Authors: Samuel Knoedler, Leonard Knoedler, Martin Kauke-Navarro, Yuval Rinkevich, Gabriel Hundeshagen, Leila Harhaus, Ulrich Kneser, Bohdan Pomahac, Dennis P. Orgill and Adriana C. Panayi
    Citation: Military Medical Research 2023 10:49
    Content type: Review Published on:

  10. Physiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations, such as firefighting, law enforcement, mili...

    Authors: Ernesto S. Nakayasu, Marina A. Gritsenko, Young-Mo Kim, Jennifer E. Kyle, Kelly G. Stratton, Carrie D. Nicora, Nathalie Munoz, Kathleen M. Navarro, Daniel Claborne, Yuqian Gao, Karl K. Weitz, Vanessa L. Paurus, Kent J. Bloodsworth, Kelsey A. Allen, Lisa M. Bramer, Fernando Montes…
    Citation: Military Medical Research 2023 10:48
    Content type: Research Published on:

  12. Hypoxic-ischemic injury is a common pathological dysfunction in clinical settings. Mitochondria are sensitive organelles that are readily damaged following ischemia and hypoxia. Dynamin-related protein 1 (Drp1...

    Authors: Shuai Hao, He Huang, Rui-Yan Ma, Xue Zeng and Chen-Yang Duan
    Citation: Military Medical Research 2023 10:46
    Content type: Review Published on:

  13. Integrated traditional Chinese medicine (TCM) and Western medicine (WM) is a new medical science grounded in the knowledge bases of both TCM and WM, which then forms a unique modern medical system in China. In...

    Authors: Ying-Hui Jin, Yan-Ping Wang, Ying-Lan Xie, Gui-Hua Tian, Xiao-Yu Zhang, Nan-Nan Shi, Ke-Hu Yang, Xin Sun, Yao-Long Chen, Da-Rong Wu, Xin-Feng Guo, Long Ge, Chen Zhao, Cheng Lu, Yin Jiang, Jing Guo…
    Citation: Military Medical Research 2023 10:45
    Content type: Position article and Guideline Published on:

  14. Auscultation is crucial for the diagnosis of respiratory system diseases. However, traditional stethoscopes have inherent limitations, such as inter-listener variability and subjectivity, and they cannot recor...

    Authors: Dong-Min Huang, Jia Huang, Kun Qiao, Nan-Shan Zhong, Hong-Zhou Lu and Wen-Jin Wang
    Citation: Military Medical Research 2023 10:44
    Content type: Review Published on:

  17. Climate change profoundly shapes the population health at the global scale. However, there was still insufficient and inconsistent evidence for the association between heat exposure and chronic kidney disease ...

    Authors: Fu-Lin Wang, Wan-Zhou Wang, Fei-Fei Zhang, Su-Yuan Peng, Huai-Yu Wang, Rui Chen, Jin-Wei Wang, Peng-Fei Li, Yang Wang, Ming-Hui Zhao, Chao Yang and Lu-Xia Zhang
    Citation: Military Medical Research 2023 10:41
    Content type: Research Published on:

  18. The treatment of chronic and non-healing wounds in diabetic patients remains a major medical problem. Recent reports have shown that hydrogel wound dressings might be an effective strategy for treating diabeti...

    Authors: Ying Chen, Xing Wang, Sheng Tao, Qi Wang, Pan-Qin Ma, Zi-Biao Li, Yun-Long Wu and Da-Wei Li
    Citation: Military Medical Research 2023 10:37
    Content type: Review Published on:

  19. Significant advancements have been made in recent years in the development of highly sophisticated skin organoids. Serving as three-dimensional models that mimic human skin, these organoids have evolved into c...

    Authors: Zi-Xuan Hong, Shun-Tian Zhu, Hao Li, Jing-Zhi Luo, Yu Yang, Yang An, Xi Wang and Kai Wang
    Citation: Military Medical Research 2023 10:40
    Content type: Review Published on:

  21. The respiratory system’s complex cellular heterogeneity presents unique challenges to researchers in this field. Although bulk RNA sequencing and single-cell RNA sequencing (scRNA-seq) have provided insights i...

    Authors: Wen-Jia Wang, Liu-Xi Chu, Li-Yong He, Ming-Jing Zhang, Kai-Tong Dang, Chen Gao, Qin-Yu Ge, Zhou-Guang Wang and Xiang-Wei Zhao
    Citation: Military Medical Research 2023 10:38
    Content type: Review Published on:

  22. Skin wounds are characterized by injury to the skin due to trauma, tearing, cuts, or contusions. As such injuries are common to all human groups, they may at times represent a serious socioeconomic burden. Cur...

    Authors: Jia-Yi Ding, Min-Jiang Chen, Ling-Feng Wu, Gao-Feng Shu, Shi-Ji Fang, Zhao-Yu Li, Xu-Ran Chu, Xiao-Kun Li, Zhou-Guang Wang and Jian-Song Ji
    Citation: Military Medical Research 2023 10:36
    Content type: Review Published on:

  23. Most bone-related injuries to grassroots troops are caused by training or accidental injuries. To establish preventive measures to reduce all kinds of trauma and improve the combat effectiveness of grassroots ...

    Authors: Ping Wu, Lin Shen, Hui-Fan Liu, Xiang-Hui Zou, Juan Zhao, Yu Huang, Yu-Fan Zhu, Zhao-Yu Li, Chao Xu, Li-Hua Luo, Zhi-Qiang Luo, Min-Hao Wu, Lin Cai, Xiao-Kun Li and Zhou-Guang Wang
    Citation: Military Medical Research 2023 10:35
    Content type: Research Published on:

  24. Triple negative breast cancer (TNBC), the most aggressive subtype of breast cancer, is characterized by a high incidence of brain metastasis (BrM) and a poor prognosis. As the most lethal form of breast cancer...

    Authors: Yi-Qun Li, Fang-Zhou Sun, Chun-Xiao Li, Hong-Nan Mo, Yan-Tong Zhou, Dan Lv, Jing-Tong Zhai, Hai-Li Qian and Fei Ma
    Citation: Military Medical Research 2023 10:34
    Content type: Research Published on:

    The Commentary to this article has been published in Military Medical Research 2023 10:42

  25. Since 2015, stroke has become the leading cause of death and disability in China, posing a significant threat to the health of its citizens as a major chronic non-communicable disease. According to the China S...

    Authors: Wen-Jun Tu and Long-De Wang
    Citation: Military Medical Research 2023 10:33
    Content type: Review Published on:

  26. Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed biomedical research and provided entirely new models to analyze every aspect of biomedical sciences during the last decade. In th...

    Authors: Bashdar Mahmud Hussen, Mohammed Fatih Rasul, Snur Rasool Abdullah, Hazha Jamal Hidayat, Goran Sedeeq Hama Faraj, Fattma Abodi Ali, Abbas Salihi, Aria Baniahmad, Soudeh Ghafouri-Fard, Milladur Rahman, Mark C. Glassy, Wojciech Branicki and Mohammad Taheri
    Citation: Military Medical Research 2023 10:32
    Content type: Review Published on:

  27. Rheumatoid arthritis (RA) is a systemic autoimmune disease that is primarily manifested as synovitis and polyarticular opacity and typically leads to serious joint damage and irreversible disability, thus adve...

    Authors: Pan Luo, Fu-Qiang Gao, Wei Sun, Jun-You Li, Cheng Wang, Qing-Yu Zhang, Zhi-Zhuo Li and Peng Xu
    Citation: Military Medical Research 2023 10:31
    Content type: Review Published on:

  29. The present study aimed to explore the potential of artificial intelligence (AI) methodology based on magnetic resonance (MR) images to aid in the management of prostate cancer (PCa). To this end, we reviewed ...

    Authors: Li-Tao Zhao, Zhen-Yu Liu, Wan-Fang Xie, Li-Zhi Shao, Jian Lu, Jie Tian and Jian-Gang Liu
    Citation: Military Medical Research 2023 10:29
    Content type: Review Published on:

  31. Sustained yet intractable immunosuppression is commonly observed in septic patients, resulting in aggravated clinical outcomes. However, due to the substantial heterogeneity within septic patients, precise ind...

    Authors: Ren-Qi Yao, Peng-Yue Zhao, Zhi-Xuan Li, Yu-Yang Liu, Li-Yu Zheng, Yu Duan, Lu Wang, Rong-Li Yang, Hong-Jun Kang, Ji-Wei Hao, Jing-Yan Li, Ning Dong, Yao Wu, Xiao-Hui Du, Feng Zhu, Chao Ren…
    Citation: Military Medical Research 2023 10:27
    Content type: Research Published on:

    The Commentary to this article has been published in Military Medical Research 2023 10:28

  32. Spinal cord injury (SCI) is a devastating and disabling medical condition generally caused by a traumatic event (primary injury). This initial trauma is accompanied by a set of biological mechanisms directed t...

    Authors: Miguel A. Ortega, Oscar Fraile-Martinez, Cielo García-Montero, Sergio Haro, Miguel Ángel Álvarez-Mon, Diego De Leon-Oliva, Ana M. Gomez-Lahoz, Jorge Monserrat, Mar Atienza-Pérez, David Díaz, Elisa Lopez-Dolado and Melchor Álvarez-Mon
    Citation: Military Medical Research 2023 10:26
    Content type: Review Published on:

  33. Globally, despite prostate cancer (PCa) representing second most prevalent malignancy in male, the precise molecular mechanisms implicated in its pathogenesis remain unclear. Consequently, elucidating the key ...

    Authors: Hong Weng, Kang-Ping Xiong, Wang Wang, Kai-Yu Qian, Shuai Yuan, Gang Wang, Fang Yu, Jun Luo, Meng-Xin Lu, Zhong-Hua Yang, Tao Liu, Xing Huang, Hang Zheng and Xing-Huan Wang
    Citation: Military Medical Research 2023 10:25
    Content type: Research Published on:

  34. Choosing the appropriate antipsychotic drug (APD) treatment for patients with schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly variable and difficult to predict due to the lac...

    Authors: Liang-Kun Guo, Yi Su, Yu-Ya-Nan Zhang, Hao Yu, Zhe Lu, Wen-Qiang Li, Yong-Feng Yang, Xiao Xiao, Hao Yan, Tian-Lan Lu, Jun Li, Yun-Dan Liao, Zhe-Wei Kang, Li-Fang Wang, Yue Li, Ming Li…
    Citation: Military Medical Research 2023 10:24
    Content type: Research Published on:

  35. Continuous renal replacement therapy (CRRT) is widely used for treating critically-ill patients in the emergency department in China. Anticoagulant therapy is needed to prevent clotting in the extracorporeal c...

    Authors: Shu-Yuan Liu, Sheng-Yong Xu, Lu Yin, Ting Yang, Kui Jin, Qiu-Bin Zhang, Feng Sun, Ding-Yu Tan, Tian-Yu Xin, Yu-Guo Chen, Xiao-Dong Zhao, Xue-Zhong Yu and Jun Xu
    Citation: Military Medical Research 2023 10:23
    Content type: Position article and Guideline Published on:

  36. Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’ anatomy. However, the interpretation of medical images can be highly subjective and dependent on the ex...

    Authors: Yuan-Peng Zhang, Xin-Yun Zhang, Yu-Ting Cheng, Bing Li, Xin-Zhi Teng, Jiang Zhang, Saikit Lam, Ta Zhou, Zong-Rui Ma, Jia-Bao Sheng, Victor C. W. Tam, Shara W. Y. Lee, Hong Ge and Jing Cai
    Citation: Military Medical Research 2023 10:22
    Content type: Review Published on:

  37. Treatment of methicillin-resistant Staphylococcus aureus (MRSA) biofilm infections in implant placement surgery is limited by the lack of antimicrobial activity of titanium (Ti) implants. There is a need to explo...

    Authors: Yong-Lin Yu, Jun-Jie Wu, Chuan-Chuan Lin, Xian Qin, Franklin R. Tay, Li Miao, Bai-Long Tao and Yang Jiao
    Citation: Military Medical Research 2023 10:21
    Content type: Research Published on:

  39. A bio-inspired strategy has recently been developed for camouflaging nanocarriers with biomembranes, such as natural cell membranes or subcellular structure-derived membranes. This strategy endows cloaked nano...

    Authors: Daniela Lopes, Joana Lopes, Miguel Pereira-Silva, Diana Peixoto, Navid Rabiee, Francisco Veiga, Omid Moradi, Zhan-Hu Guo, Xiang-Dong Wang, João Conde, Pooyan Makvandi and Ana Cláudia Paiva-Santos
    Citation: Military Medical Research 2023 10:19
    Content type: Review Published on:

  42. Biomimetic materials have emerged as attractive and competitive alternatives for tissue engineering (TE) and regenerative medicine. In contrast to conventional biomaterials or synthetic materials, biomimetic s...

    Authors: Shuai Liu, Jiang-Ming Yu, Yan-Chang Gan, Xiao-Zhong Qiu, Zhe-Chen Gao, Huan Wang, Shi-Xuan Chen, Yuan Xiong, Guo-Hui Liu, Si-En Lin, Alec McCarthy, Johnson V. John, Dai-Xu Wei and Hong-Hao Hou
    Citation: Military Medical Research 2023 10:16
    Content type: Review Published on:

  43. Reconstruction of damaged tissues requires both surface hemostasis and tissue bridging. Tissues with damage resulting from physical trauma or surgical treatments may have arbitrary surface topographies, making...

    Authors: Yao-Ting Xue, Ming-Yu Chen, Jia-Sheng Cao, Lei Wang, Jia-Hao Hu, Si-Yang Li, Ji-Liang Shen, Xin-Ge Li, Kai-Hang Zhang, Shu-Qiang Hao, Sarun Juengpanich, Si-Bo Cheng, Tuck-Whye Wong, Xu-Xu Yang, Tie-Feng Li, Xiu-Jun Cai…
    Citation: Military Medical Research 2023 10:15
    Content type: Research Published on:

  45. Vascular hyporeactivity and leakage are key pathophysiologic features that produce multi-organ damage upon sepsis. We hypothesized that pericytes, a group of pluripotent cells that maintain vascular integrity ...

    Authors: Zi-Sen Zhang, Yi-Yan Liu, Shuang-Shuang He, Dai-Qin Bao, Hong-Chen Wang, Jie Zhang, Xiao-Yong Peng, Jia-Tao Zang, Yu Zhu, Yue Wu, Qing-Hui Li, Tao Li and Liang-Ming Liu
    Citation: Military Medical Research 2023 10:13
    Content type: Research Published on:

  46. The rapid development of genome editing technology has brought major breakthroughs in the fields of life science and medicine. In recent years, the clustered regularly interspaced short palindromic repeats (CR...

    Authors: Zhen-Hua Li, Jun Wang, Jing-Ping Xu, Jian Wang and Xiao Yang
    Citation: Military Medical Research 2023 10:12
    Content type: Review Published on:

  47. Gulf War Illness (GWI) encompass a spectrum of maladies specific to troops deployed during the Persian Gulf War (1990–1991). There are several hypothesized factors believed to contribute to GWI, including (but...

    Authors: Rami Elhaj and Joseph M. Reynolds
    Citation: Military Medical Research 2023 10:11
    Content type: Perspective Published on:

  48. Drug discovery is a crucial part of human healthcare and has dramatically benefited human lifespan and life quality in recent centuries, however, it is usually time- and effort-consuming. Structural biology ha...

    Authors: Kong-Fu Zhu, Chuang Yuan, Yong-Ming Du, Kai-Lei Sun, Xiao-Kang Zhang, Horst Vogel, Xu-Dong Jia, Yuan-Zhu Gao, Qin-Fen Zhang, Da-Ping Wang and Hua-Wei Zhang
    Citation: Military Medical Research 2023 10:10
    Content type: Review Published on:

  49. Gene therapy has shown great potential to treat various diseases by repairing the abnormal gene function. However, a great challenge in bringing the nucleic acid formulations to the market is the safe and effe...

    Authors: Yu-Qi Zhang, Ran-Ran Guo, Yong-Hu Chen, Tian-Cheng Li, Wen-Zhen Du, Rong-Wu Xiang, Ji-Bin Guan, Yu-Peng Li, Yuan-Yu Huang, Zhi-Qiang Yu, Yin Cai, Peng Zhang and Gui-Xia Ling
    Citation: Military Medical Research 2023 10:9
    Content type: Review Published on:

  50. Fungi and bacteria afflict humans with innumerous pathogen-related infections and ailments. Most of the commonly employed microbicidal agents target commensal and pathogenic microorganisms without discriminati...

    Authors: Pooyan Makvandi, Hao Song, Cynthia K. Y. Yiu, Rossella Sartorius, Ehsan Nazarzadeh Zare, Navid Rabiee, Wei-Xi Wu, Ana Cláudia Paiva-Santos, Xiang-Dong Wang, Cheng-Zhong Yu and Franklin R. Tay
    Citation: Military Medical Research 2023 10:8
    Content type: Review Published on:

    The Correction to this article has been published in Military Medical Research 2023 10:30

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  • ISSN: 2054-9369 (electronic)

Military Medical Research

ISSN: 2054-9369