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  1. Sepsis involves life-threatening organ dysfunction and is caused by a dysregulated host response to infection. No specific therapies against sepsis have been reported. Celastrol (Cel) is a natural anti-inflamm...

    Authors: Piao Luo, Qian Zhang, Tian-Yu Zhong, Jia-Yun Chen, Jun-Zhe Zhang, Ya Tian, Liu-Hai Zheng, Fan Yang, Ling-Yun Dai, Chang Zou, Zhi-Jie Li, Jing-Hua Liu and Ji-Gang Wang
    Citation: Military Medical Research 2022 9:22
  2. Granulomatous lobular mastitis (GLM) is a rare and chronic benign inflammatory disease of the breast. Difficulties exist in the management of GLM for many front-line surgeons and medical specialists who care f...

    Authors: Qian-Qian Yuan, Shu-Xuan Xiao, Omar Farouk, Yu-Tang Du, Fereshte Sheybani, Qing Ting Tan, Sami Akbulut, Kenan Cetin, Afsaneh Alikhassi, Rami Jalal Yaghan, Irmak Durur-Subasi, Fatih Altintoprak, Tae Ik Eom, Fatih Alper, Mustafa Hasbahceci, David Martínez-Ramos…
    Citation: Military Medical Research 2022 9:20
  3. Stemness and chemoresistance contribute to cervical cancer recurrence and metastasis. In the current study, we determined the relevant players and role of N6-methyladenine (m6A) RNA methylation in cervical cancer...

    Authors: Xian Lin, Feng Wang, Jian Chen, Jing Liu, Yi-Bin Lin, Li Li, Chuan-Ben Chen and Qin Xu
    Citation: Military Medical Research 2022 9:19
  4. Spinal cord injury (SCI) is a serious traumatic disease of the central nervous system, which can give rise to the loss of motor and sensory function. Due to its complex pathological mechanism, the treatment of...

    Authors: Yan Wang, Hong-Qian Lv, Xuan Chao, Wen-Xin Xu, Yun Liu, Gui-Xia Ling and Peng Zhang
    Citation: Military Medical Research 2022 9:16
  5. Currently, there is no formal consensus regarding a standard classification for gastric cancer (GC) patients with < 16 retrieved lymph nodes (rLNs). Here, this study aimed to validate a practical lymph node (L...

    Authors: Wei Wang, Yu-Jie Yang, Ri-Hong Zhang, Jing-Yu Deng, Zhe Sun, Sharvesh Raj Seeruttun, Zhen-Ning Wang, Hui-Mian Xu, Han Liang and Zhi-Wei Zhou
    Citation: Military Medical Research 2022 9:15
  6. Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Tran...

    Authors: Xian-Tao Zeng, Ying-Hui Jin, Tong-Zu Liu, Fang-Ming Chen, De-Gang Ding, Meng Fu, Xin-Quan Gu, Bang-Min Han, Xing Huang, Zhi Hou, Wan-Li Hu, Xin-Li Kang, Gong-Hui Li, Jian-Xing Li, Pei-Jun Li, Chao-Zhao Liang…
    Citation: Military Medical Research 2022 9:14
  7. Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogrammi...

    Authors: Shuai-Fei Ji, Lai-Xian Zhou, Zhi-Feng Sun, Jiang-Bing Xiang, Shao-Yuan Cui, Yan Li, Hua-Ting Chen, Yi-Qiong Liu, Huan-Huan Gao, Xiao-Bing Fu and Xiao-Yan Sun
    Citation: Military Medical Research 2022 9:13
  8. Studies had shown many diseases affect the stability of human microbiota, but how this relates to benign prostatic hyperplasia (BPH) has not been well understood. Hence, this study aimed to investigate the reg...

    Authors: Lu-Yao Li, Jie Han, Lan Wu, Cheng Fang, Wei-Guang Li, Jia-Min Gu, Tong Deng, Chang-Jiang Qin, Jia-Yan Nie and Xian-Tao Zeng
    Citation: Military Medical Research 2022 9:12
  9. Traditional diagnostic strategies for infectious disease detection require benchtop instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a highly miniaturized, automatic...

    Authors: Xin Wang, Xian-Zhe Hong, Yi-Wei Li, Ying Li, Jie Wang, Peng Chen and Bi-Feng Liu
    Citation: Military Medical Research 2022 9:11
  10. Novel advances in the field of brain imaging have enabled the unprecedented clinical application of various imaging modalities to facilitate disease diagnosis and treatment. Electrical impedance tomography (EI...

    Authors: Xi-Yang Ke, Wei Hou, Qi Huang, Xue Hou, Xue-Ying Bao, Wei-Xuan Kong, Cheng-Xiang Li, Yu-Qi Qiu, Si-Yi Hu and Li-Hua Dong
    Citation: Military Medical Research 2022 9:10
  11. Ultrasound-triggered microbubble destruction (UTMD) is a widely used noninvasive technology in both military and civilian medicine, which could enhance radiosensitivity of various tumors. However, little infor...

    Authors: Ying He, Xun-Hu Dong, Qiong Zhu, Ya-Li Xu, Ming-Liang Chen and Zheng Liu
    Citation: Military Medical Research 2022 9:9
  12. Early diagnosis and classification of infections increase the cure rate while decreasing complications, which is significant for severe infections, especially for war surgery. However, traditional methods rely...

    Authors: Bin-Feng Yin, Xin-Hua Wan, Ming-Zhu Yang, Chang-Cheng Qian and A. S. M. Muhtasim Fuad Sohan
    Citation: Military Medical Research 2022 9:8
  13. Airway inflammation is the core pathological process of asthma, with the key inflammatory regulators incompletely defined. Recently, fibroblast growth factor 2 (FGF2) has been reported to be an inflammatory re...

    Authors: Yuan-Yang Tan, Hui-Qin Zhou, Yu-Jing Lin, Liu-Tong Yi, Zhuang-Gui Chen, Qing-Dong Cao, Yan-Rong Guo, Zhao-Ni Wang, Shou-Deng Chen, Yang Li, De-Yun Wang, Yong-Kang Qiao and Yan Yan
    Citation: Military Medical Research 2022 9:7
  14. In sepsis, vitamin D binding protein (VDBP) has been shown to be low-expressed. The current study examined the relationship between serum VDBP level and liver injury in sepsis patients, as well as in a mouse m...

    Authors: Kun Xiao, Du-Chao Zhang, Ye Hu, Li-Cheng Song, Jian-Qiao Xu, Wan-Xue He, Pan Pan, Yu-Wei Wang and Li-Xin Xie
    Citation: Military Medical Research 2022 9:4
  15. Bacteria can evolve rapidly by acquiring new traits such as virulence, metabolic properties, and most importantly, antimicrobial resistance, through horizontal gene transfer (HGT). Multidrug resistance in bact...

    Authors: Zhen Shen, Christoph M. Tang and Guang-Yu Liu
    Citation: Military Medical Research 2022 9:3
  16. Since the end of 2019, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. The RNA genome of SARS-CoV-2, which is highly infectious ...

    Authors: Xue-Liang Peng, Ji-Si-Yu Cheng, Hai-Lun Gong, Meng-Di Yuan, Xiao-Hong Zhao, Zibiao Li and Dai-Xu Wei
    Citation: Military Medical Research 2021 8:67
  17. The healing of bone defects can be challenging for clinicians to manage, especially after exposure to ionizing radiation. In this regard, radiation therapy and accidental exposure to gamma (γ)-ray radiation ha...

    Authors: Wei Hu, Jia-Wu Liang, Song Liao, Zhi-Dong Zhao, Yu-Xing Wang, Xiao-Fei Mao, Si-Wei Hao, Yi-Fan Wang, Heng Zhu and Bin Guo
    Citation: Military Medical Research 2021 8:61
  18. Musculoskeletal injuries (MSkIs) are a leading cause of health care utilization, as well as limited duty and disability in the US military and other armed forces. MSkIs affect members of the military during in...

    Authors: Stefan Sammito, Vedran Hadzic, Thomas Karakolis, Karen R. Kelly, Susan P. Proctor, Ainars Stepens, Graham White and Wes O. Zimmermann
    Citation: Military Medical Research 2021 8:66
  19. In the case of a terrorist attack by a “dirty bomb”, blast injuries, external irradiation and the incorporation of radioactivity are to be expected. Departing from information about the radiological attack sce...

    Authors: Alexis Rump, Stefan Eder, Cornelius Hermann, Andreas Lamkowski, Patrick Ostheim, Michael Abend and Matthias Port
    Citation: Military Medical Research 2021 8:65
  20. Urinary tract infections (UTI), urolithiasis, and benign prostatic hyperplasia (BPH) are three of the most common nonmalignant conditions in urology. However, there is still a lack of comprehensive and updated...

    Authors: Cong Zhu, Dan-Qi Wang, Hao Zi, Qiao Huang, Jia-Min Gu, Lu-Yao Li, Xing-Pei Guo, Fei Li, Cheng Fang, Xiao-Dong Li and Xian-Tao Zeng
    Citation: Military Medical Research 2021 8:64
  21. Triple-negative breast cancer (TNBC) is the most aggressive subtype and occurs in approximately 15–20% of diagnosed breast cancers. TNBC is characterized by its highly metastatic and recurrent features, as wel...

    Authors: Dan-Dan Zhou, Wei-Qi Bai, Xiao-Tian Zhai, Li-Ping Sun, Yong-Su Zhen, Zhuo-Rong Li and Qing-Fang Miao
    Citation: Military Medical Research 2021 8:63
  22. Disruption of the blood–brain barrier (BBB) after a stroke can lead to brain injury and neurological impairment. Previous work confirmed the involvement of the immunoproteasome subunit of low molecular mass pe...

    Authors: Xing-Yong Chen, Shao-Fen Wan, Nan-Nan Yao, Ze-Jing Lin, Yan-Guang Mao, Xiao-Hua Yu and Yin-Zhou Wang
    Citation: Military Medical Research 2021 8:62
  23. The burden of kidney, bladder, and prostate cancers has changed in recent decades. This study aims to investigate the global and regional burden of, and attributable risk factors for genitourinary cancers duri...

    Authors: Hao Zi, Shao-Hua He, Xie-Yuan Leng, Xiao-Feng Xu, Qiao Huang, Hong Weng, Cong Zhu, Lu-Yao Li, Jia-Min Gu, Xu-Hui Li, Dao-Jing Ming, Xiao-Dong Li, Shuai Yuan, Xing-Huan Wang, Da-Lin He and Xian-Tao Zeng
    Citation: Military Medical Research 2021 8:60
  24. Administration of propofol, an intravenous anesthetic with antioxidant property, immediately at the onset of post-ischemic reperfusion (propofol postconditioning, P-PostC) has been shown to confer cardioprotec...

    Authors: Rong-Hui Han, He-Meng Huang, Hong Han, Hao Chen, Fei Zeng, Xiang Xie, Dan-Yong Liu, Yin Cai, Liang-Qing Zhang, Xin Liu, Zheng-Yuan Xia and Jing Tang
    Citation: Military Medical Research 2021 8:58
  25. Targeting immune checkpoints has achieved great therapeutic effects in the treatment of early-stage tumors. However, most patients develop adaptive resistance to this therapy. The latest evidence demonstrates ...

    Authors: Cheng Xing, Heng Li, Rui-Juan Li, Le Yin, Hui-Fang Zhang, Zi-Neng Huang, Zhao Cheng, Ji Li, Zhi-Hua Wang and Hong-Ling Peng
    Citation: Military Medical Research 2021 8:56
  26. Mitochondria have been shown to play vital roles during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) development. Currently, it is unclear whet...

    Authors: Yi Wu, Xian-Hui Wang, Xi-Hua Li, Li-Yuan Song, Shi-Long Yu, Zhi-Cheng Fang, Yu-Quan Liu, Le-Yong Yuan, Chun-Yan Peng, Shen-Yi Zhang, Wang Cheng, Hong-Chao Ma, Li-Feng Wang, Jun-Ming Tang, Yun-Fu Wang and Fu-Yun Ji
    Citation: Military Medical Research 2021 8:57
  27. The military population face a unique set of risk factors that may increase the risk of being diagnosed with dementia. Traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) have a higher preva...

    Authors: Zara Raza, Syeda F. Hussain, Suzanne Ftouni, Gershon Spitz, Nick Caplin, Russell G. Foster and Renata S. M. Gomes
    Citation: Military Medical Research 2021 8:55
  28. Despite the widespread use of malaria rapid diagnostic test (RDT) in clinical practice, there are a lot of challenges. We conducted a secondary analysis of 129 malaria RDT data from rounds 5–8 of the World Hea...

    Authors: Biao Xu, Bo Tu, Fang Chu, Mohamed Jalloh, Jin-Song Mu, Jun-Jie Zheng and Wei-Wei Chen
    Citation: Military Medical Research 2021 8:52
  29. Periodontitis has been proposed as a novel risk factor of genitourinary cancers: although periodontitis and genitourinary cancers are two totally distinct types of disorders, epidemiological and clinical studi...

    Authors: Shuai Yuan, Cheng Fang, Wei-Dong Leng, Lan Wu, Bing-Hui Li, Xing-Huan Wang, Hailiang Hu and Xian-Tao Zeng
    Citation: Military Medical Research 2021 8:54
  30. To determine the prevalence and clinical features of olfactory and taste disorders among coronavirus disease 2019 (COVID-19) patients in China. A cross-sectional study was performed in Wuhan from April 3, 2020...

    Authors: Jian-Hui Li, Yi Sun, Mei-Rong Li, Hu Yuan, Chang-Liang Yang, Cheng-Cheng Huang, Feng-Jie Zhou, Rui-Yao Chen, Lei-Bo Zhang, Ning Yu, Qiong Liu, Jing-Jing He, Xue-Jun Zhou, Xiao-Bing Fu and Shi-Ming Yang
    Citation: Military Medical Research 2021 8:51
  31. The management of bacterial infections is becoming a major clinical challenge due to the rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome antibiotic resistance, antimicro...

    Authors: Qi-Yu Zhang, Zhi-Bin Yan, Yue-Ming Meng, Xiang-Yu Hong, Gang Shao, Jun-Jie Ma, Xu-Rui Cheng, Jun Liu, Jian Kang and Cai-Yun Fu
    Citation: Military Medical Research 2021 8:48
  32. Retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5) sense viral RNA and activate antiviral immune responses. Herein we investigate their functions in human epithelia...

    Authors: Duo-Meng Yang, Ting-Ting Geng, Andrew G. Harrison and Peng-Hua Wang
    Citation: Military Medical Research 2021 8:49
  33. SARS-CoV-2 is a newly identified member of the coronavirus family that has caused the Coronavirus disease 2019 (COVID-19) pandemic. This rapidly evolving and unrelenting SARS-CoV-2 has disrupted the lives and ...

    Authors: Natalie Yan-Lin Pang, Alexander Shao-Rong Pang, Vincent T. Chow and De-Yun Wang
    Citation: Military Medical Research 2021 8:47
  34. Malondialdehyde (MDA) is a candidate general marker of oxidative stress (OS). We sought to assess the relation of MDA to Gulf War illness (GWI) and to a variety of exposures.

    Authors: Beatrice Alexandra Golomb, Sridevi Devaraj, Alexis K. Messner, Hayley Jean Koslik, Jun Hee Han and Barnabas Yik
    Citation: Military Medical Research 2021 8:46
  35. Many high quality studies have emerged from public databases, such as Surveillance, Epidemiology, and End Results (SEER), National Health and Nutrition Examination Survey (NHANES), The Cancer Genome Atlas (TCG...

    Authors: Wen-Tao Wu, Yuan-Jie Li, Ao-Zi Feng, Li Li, Tao Huang, An-Ding Xu and Jun Lyu
    Citation: Military Medical Research 2021 8:44
  36. Service members are at risk for sleep and psychological conditions affecting their readiness. Chronotype (“morningness” or “eveningness”) is strongly associated with sleep, health and performance. The objectiv...

    Authors: Elizabeth M. Harrison, Alexandra P. Easterling, Emily A. Schmied, Suzanne L. Hurtado and Gena L. Glickman
    Citation: Military Medical Research 2021 8:43
  37. War and combat exposure pose great risks to the vision system. More recently, vision related deficiencies and impairments have become common with the increased use of powerful explosive devices and the subsequ...

    Authors: Syeda F. Hussain, Zara Raza, Andrew T. G. Cash, Thomas Zampieri, Robert A. Mazzoli, Randy H. Kardon and Renata S. M. Gomes
    Citation: Military Medical Research 2021 8:42
  38. The clinical efficiency of routine oxygen therapy is uncertain in patients with acute heart failure (AHF) who do not have hypoxemia. The aim of this study was to investigate the association between oxygen ther...

    Authors: Yue Yu, Ren-Qi Yao, Yu-Feng Zhang, Su-Yu Wang, Wang Xi, Jun-Nan Wang, Xiao-Yi Huang, Yong-Ming Yao and Zhi-Nong Wang
    Citation: Military Medical Research 2021 8:38