Table 2 Basic and clinical information on different treatments for acute ischemic stroke
Characteristics | IVT (n = 188,648) | MT (n = 49,845) | Bridging (IVR + MT) (n = 14,087) |
|---|---|---|---|
Sex-male [n (%)] | 121,574 (64.4) | 31,999 (64.2) | 9049 (64.2) |
Age [years, (mean ± SD)] | 68.7 ± 11.4 | 68.3 ± 11.4 | 68.7 ± 11.4 |
Age [n (%)] | |||
≤ 40 years | 844 (0.5) | 297 (0.6) | 80 (0.6) |
40–60 years | 43,148 (22.9) | 11,825 (23.7) | 3221 (22.9) |
≥ 60 years | 144,656 (76.7) | 37,723 (75.7) | 10,786 (76.6) |
Race-Chinese Han [n (%)] | 183,857 (97.5) | 48,622 (97.6) | 13,706 (97.3) |
Hospital grade-tertiary [n (%)] | 142,550 (75.6) | 47,871 (96.1) | 13,121 (93.2) |
Seven Regions of China [n (%)] | |||
North China | 36,397 (19.3) | 4590 (9.2) | 1226 (8.7) |
Northeast | 21,583 (11.4) | 4536 (9.1) | 1060 (7.5) |
Central China | 55,668 (29.5) | 17,654 (35.4) | 5081 (36.1) |
East China | 33,822 (17.9) | 8023 (16.1) | 2310 (16.4) |
South China | 13,751 (7.3) | 7320 (14.7) | 2139 (15.2) |
Southwest | 20,082 (10.7) | 5083 (10.2) | 1567 (11.1) |
Northwest | 7345 (3.9) | 2639 (5.3) | 704 (5) |
Time from onset to hospital arrival within 2 h [n (%)] | 135,543 (75.4) | 21,049 (47.3) | 10,656 (79.8) |
Transported to hospital by EMS [n (%)] | 69,603 (36.9) | 24,846 (49.9) | 7633 (54.2) |
BMI (kg/m2, mean ± SD) | 23.9 ± 24.4 | 23.9 ± 3.7 | 23.8 ± 3.5 |
Systolic pressure (mmHg, mean ± SD) | 153.0 ± 23.1 | 148.9 ± 24.6 | 149.4 ± 24.2 |
Diastolic pressure (mmHg, mean ± SD) | 87.5 ± 14.1 | 85.9 ± 15.1 | 86.0 ± 14.8 |
Toast classification in ischemic stroke | |||
1-LAA | 93,478 (49.6) | 31,062 (62.3) | 8809 (62.5) |
2-CE | 23,104 (12.3) | 14,244 (28.6) | 4191 (29.8) |
3-SVO | 63,321 (33.6) | 2163 (4.3) | 518 (3.7) |
4-SOE | 1394 (0.7) | 678 (1.4) | 149 (1.1) |
5-SUE | 7337 (3.9) | 1687 (3.4) | 419 (3) |
NIHSS score at admission [median (IQR)] | 6 (3–12) | 15 (10–20) | 15 (11–22) |
Acute phase treatment | |||
DNT (min, mean ± SD) | 166.0 ± 1325.3 | – | 64.9 ± 849.8 |
ONT (min, mean ± SD) | 248.6 ± 5933.7 | – | 171.5 ± 653.5 |
Thrombolytic complications [n (%)] | 21,772 (11.5) | – | 1251 (8.9) |
Intracranial hemorrhage [n (%)] | 6089 (3.2) | – | 542 (3.8) |
DPT (min, mean ± SD) | – | 322.6 ± 6235.9 | 195.4 ± 1057.6 |
OPT (min, mean ± SD) | – | 562.9 ± 6702.7 | 297.6 ± 796.8 |
Thrombectomy complications [n (%)] | – | 6893 (13.8) | 2152 (15.3) |
Intracranial hemorrhage [n (%)] | – | 3861 (7.7) | 1273 (9.0) |
Reasons for not thrombolysis—over time window [n (%)] | – | 16,608 (33.3) | - |
Length of stay (d, mean ± SD) | 11.2 ± 18.4 | 14.6 ± 26.0 | 14.7 ± 16.1 |
Discharge outcome [n (%)] | |||
Medical discharge | 159,101 (84.3) | 36,585 (73.4) | 10,382 (73.7) |
Medical order transfer | 6537 (3.5) | 1843 (3.7) | 488 (3.5) |
Transfer to grass-roots hospitals | 3407 (1.8) | 1760 (3.5) | 464 (3.3) |
Discharge against medical advice | 13,542 (7.2) | 5733 (11.5) | 1549 (11.0) |
Death | 3233 (1.7) | 2511 (5.0) | 821 (5.8) |
Unclear | 2828 (1.5) | 1413 (2.8) | 383 (2.7) |