Table 9 Application of RCA in different CRRT modes
Mode | Solute removed | Replacement fluid or dialysate | Characteristics of CCC eliminated by semi permeable membrane | Feasibility of RCA |
|---|---|---|---|---|
SCUF | Negligible | No | CCC cannot be effectively eliminated by semi-permeable membrane, and too much CCC entering the systemic circulation is prone to causing metabolic alkalosis | Not suitable |
CVVH | Medium/small molecule | Yes | The flow rate of replacement fluid is limited by transmembrane pressure and filtration fraction | Yes |
CVVHD | Small molecule | Yes | Not limited by transmembrane pressure and filtration fraction and can increase dialysate flow rate to increase CCC clearance through semi-permeable membrane. Citrate replacement solution cannot be used alone | Yes |
CVVHDF | Medium/small molecule | Yes | Has advantages of both CVVH and CVVHD, and can achieve a larger replacement fluid or dialysate flow rate, which is conducive to the management of any metabolic complications of RCA | Yes |