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Fig. 3 | Military Medical Research

Fig. 3

From: Management of regional citrate anticoagulation for continuous renal replacement therapy: guideline recommendations from Chinese emergency medical doctor consensus

Fig. 3

Schematic diagram of RCA in the CRRT system. Citrate is infused into the extracorporeal circulation before filter. Citrate-calcium complexes (CCC) is formed by the chelation reaction of ionized calcium (iCa) and Citrate3−. Partial CCC and iCa are removed by the filter. As a result, iCa in the filter is rapidly reduced to below 0.4 mmol/L, thus preventing clotting. The concentration of iCa in the filter is routinely monitored at the site behind the filter. Before the blood is returned to the body, additional iCa is infused to the blood in order to replenish the calcium removed to effluent by the filter. RCA regional citrate anticoagulation, CRRT continuous renal replacement therapy

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Military Medical Research

ISSN: 2054-9369