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Fig. 5 | Military Medical Research

Fig. 5

From: Elimination of methicillin-resistant Staphylococcus aureus biofilms on titanium implants via photothermally-triggered nitric oxide and immunotherapy for enhanced osseointegration

Fig. 5

Bone regeneration in an MRSA-infected femoral defect implantation model in vivo. a Micro-CT images of new bone. Scale bar = 400 μm. b Quantitative analysis of newly-formed bone tissues based on three‑dimensional (3D) reconstruction images of micro-CT, including bone volume/total volume (BV/TV), trabecular thickness (Tb.Th), and trabecular number (Tb.N) after 4 weeks. c Representative images of HE and Masson’s trichrome staining at bone-implant interface. Scale bar = 200 μm. **P < 0.01; Ti titanium, PDA polydopamine nanoparticles, SNP sodium nitroprusside, OGP osteogenic growth peptide, HE hematoxylin and eosin

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