Table 1 SARS-CoV-2 variants (the data are from the WHO website, as of October 12, 2021)
From: Advances in the design and development of SARS-CoV-2 vaccines
WHO label | Pango lineages | Additional amino acid changes monitoreda | Earliest documented samples | Date of designation |
|---|---|---|---|---|
Variants of Concern (VOC) | Â | Â | Â | Â |
Alpha | B.1.1.7 | + S: 484K + S: 452R | 18-Dec-2020 | |
Beta | B.1.351 B.1.351.2 B.1.351.3 | + S: L18F | 18-Dec-2020 | |
Gamma | P.1 P.1.1 P.1.2 | + S: 681H | Brazil, Nov-2020 [46] | 11-Jan-2021 |
Delta | B.1.617.2 AY.1 AY.2 | + S: 417N | India, Oct-2020 [47] | VOI: 4-Apr-2021 VOC: 11-May-2021 |
Variants of Interest (VOI) | Â | Â | Â | Â |
Eta | B.1.525 | Â | Multiple countries, Dec-2020 | 17-Mar-2021 |
Iota | B.1.526 | Â | United States of America, Nov-2020 | 24-Mar-2021 |
Kappa | B.1.617.1 | Â | India, Oct-2020 [48] | 4-Apr-2021 |
Lambda | C.37 | Â | Peru, Dec-2020 | 14-Jun-2021 |
Mu | B.1.621 | Â | Colombia, Jan-2021 | 30-Aug-2021 |
Reclassifying VOIs/VOCs | Â | Â | Â | Â |
| Â | B.1.427 B.1.429b | Â | United States of America, Mar-2020 | VOI: 5-Mar-2021 Alert: 6-Jul-2021 |
| Â | P.2b | Â | Brazil, Apr-2020 | VOI: 17-Mar-2021 Alert: 6-Jul-2021 |
| Â | P.3b | Â | Philippines, Jan-2021 | VOI: 24-Mar-2021 Alert: 6-Jul-2021 |
| Â | R.1 R.2 | Â | Multiple countries, Jan-2021 | 07-Apr-2021 |
| Â | B.1.466.2 | Â | Indonesia, Nov-2020 | 28-Apr-2021 |
| Â | B.1.621 | Â | Colombia, Jan-2021 | 26-May-2021 |
| Â | AV.1 | Â | United Kingdom, Mar-2021 | 26-May-2021 |
| Â | B.1.1.318 | Â | Multiple countries, Jan-2021 | 02-Jun-2021 |
| Â | B.1.1.519 | Â | Multiple countries, Nov-2021 | 02-Jun-2021 |
| Â | AT.1 | Â | Russian Federation, Jan-2021 | 09-Jun-2021 |
| Â | C.36.3 C.36.3.1 | Â | Multiple countries, Jan-2021 | 16-Jun-2021 |
| Â | B.1.214.2 | Â | Multiple countries, Nov-2020 | 30-Jun-2021 |
| Â | B.1.1.523 | Â | Multiple countries, May-2020 | 14-Jul-2021 |
| Â | B.1.620 | Â | Multiple countries, November 2020 | 14-Jul-2021 |
| Â | C.1.2 | Â | South Africa, May 2021 | 01-Sep-2021 |
| Â | B.1.617.1b | Â | India, Oct-2020 | VOI: 4-Apr-2021 VUM: 20-Sep-2021 |
| Â | B.1.526b | Â | United States of America, Nov-2020 | VOI: 24-Mar-2021 VUM: 20-Sep-2021 |
| Â | B.1.525b | Â | Multiple countries, Dec-2020 | VOI:17-Mar-2021 VUM: 20-Sep-2021 |
| Â | B.1.630 | Â | Dominican Republic, Mar-2021 | 12-Oct-2021 |