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Fig. 3 | Military Medical Research

Fig. 3

From: Melatonin attenuates radiation-induced cortical bone-derived stem cells injury and enhances bone repair in postradiation femoral defect model

Fig. 3

Effect of melatonin on intracellular oxidative stress in postradiation CBSCs. a Intracellular ROS levels were detected and quantified by flow cytometry after DCFH-DA staining. b Levels of oxidative stress-related markers in CBSCs. Compared with control, *P < 0.05; compared with IR, #P < 0.05. IR irradiation, IR + LMLT irradiation plus low 1 μmol/L melatonin treatment, IR + MMLT irradiation plus medium 10 μmol/L melatonin treatment, IR + HMLT irradiation plus high 100 μmol/L melatonin treatment, CBSCs cortical bone-derived stem cells, ROS reactive oxygen species, DCFH-DA 2,7-dichlorodihydrofluorescein diacetate, DCF 2',7'-dichlorofluorescein, MDA malondialdehyde, SOD superoxide dismutase, GSH/GSSG glutathione/oxidized glutathione

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Military Medical Research

ISSN: 2054-9369