Fig. 6

TLR5 signaling contributes to hepatic lipid accumulation induced by PHx. a H&E staining, Oil Red O staining, and quantification of positive areas of WT and Tlr5^−/− mouse livers after PHx. Triglyceride, NEFA, and cholesterol levels in liver extracts (b) and serum (c) were measured in WT and Tlr5^−/− mice at the indicated times after PHx. d Analysis of hepatic triglyceride, NEFA, and cholesterol levels in PBS and CBLB502 treated mice after PHx. e H&E staining, Oil Red O staining, and quantification of positive areas of PBS and CBLB502 treated mouse livers after PHx. Black arrows indicate hepatic lipids. Results are expressed as the mean ± SEM. Data are derived from two or three independent experiments with similar results. n = 5–7. *P < 0.05, **P < 0.01, ***P < 0.001