Fig. 7

Immunohistochemical evaluation of epidermal growth factor (EGF) combined with vacuum sealing drainage (VSD) in the treatment of wounds. a. Immunohistochemical staining of collagen I in the wound 10 d after the operation; the following picture is an enlargement of the local area from the above picture. b. Immunohistochemical staining of collagen III in the wound 10 d after the operation; the following picture is an enlargement of the local area from the above picture. c. The ratio of collagen I/III in the wound area 10 d after the operation (Control: 3.26 ± 0.22, VSD: 2.85 ± 0.17, V + E 10 min: 2.24 ± 0.12, V + E 30 min: 2.05 ± 0.17). The scale bar in the global image above is 500 μm, and the scale bar in the enlarged image below is 70 μm. Data are shown as means ± SD, **P < 0.01