Table 1 Patient characteristics, severity scores and resuscitation strategies
From: Acute kidney injury in severely injured patients admitted to the intensive care unit
Variable | Non-AKI group (n = 240) | AKI group (n = 75) | Total (n = 315) | P |
|---|---|---|---|---|
Male [n(%)] | 206 (85.8) | 69 (92.0) | 275 (87.3) | 0.17 |
Age [years, M (IQR)] | 27.0 (22.0–38.5) | 33.0 (22.0–45.0) | 28.0 (22.0–41.0) | 0.15 |
Trauma mechanism [n(%)] | 0.01 | |||
Penetrating | 66 (27.5) | 29 (38.7) | 95 (30.2) | |
Blunt | 130 (54.2) | 42 (56.0) | 172 (54.6) | |
Explosion | 44 (18.3) | 4 (5.3) | 48 (15.2) | |
SBP [mmHg, M (IQR)] | 119 (98–132) | 116 (95–138) | 117 (98–133) | 0.97 |
BR [breathings/min, M (IQR)] | 21 (18–24) | 20 (18–26) | 21 (18–24) | 0.62 |
Glasgow coma score [M (IQR)] | 15 (7–15) | 14 (6–15) | 15 (7–15) | 0.11 |
AIS head [M (IQR)] | 1 (0–4) | 0 (0–3) | 1 (0–4) | 0.18 |
AIS face [M (IQR)] | 0 (0–1) | 0 (0–0) | 0 (0–1) | 0.04 |
AIS thorax [M (IQR)] | 0 (0–3) | 3 (0–4) | 0 (0–3) | < 0.01 |
AIS abdomen/pelvis [M (IQR)] | 0 (0–2) | 0 (0–3) | 0 (0–2) | 0.01 |
AIS extremity [M (IQR)] | 2 (0–3) | 2 (0–3) | 2 (0–3) | 0.37 |
AIS external [M (IQR)] | 1 (0–1) | 1 (0–1) | 0 (0–1) | 0.05 |
ISS [M (IQR)] | 20 (14–27) | 26 (19–34) | 21 (16–29) | < 0.01 |
RTS [M (IQR)] | 7.55 (5.97–7.84) | 7.55 (5.03–7.84) | 7.55 (5.97–7.84) | 0.23 |
APACHE II [M (IQR)] | 13 (8.5–18.5) | 18 (10–27) | 14 (9–21) | < 0.01 |
CK maximun [M (IQR)] | 1924 (726–4940) | 2508 (999–10,418) | 2081 (794–5785) | 0.02 |
CK > 5000 [n(%)] | 37 (15.4) | 23 (30.7) | 60 (19.0) | < 0.01 |
Initial acid lactic [M (IQR)] | 2.98 (1.76–4.56) | 4.33 (2.13–6.09) | 3.09 (1.77–4.99) | < 0.01 |
Initial base deficit [M (IQR)] | 7.05 (4.5–9.7) | 8.7 (5.8–12.4) | 7.4 (4.9–10.2) | < 0.01 |
Fluid balance, first 24 h [Lt., M (IQR)] | 1.96 (0.64–3.42) | 3.37 (1.57–5.49) | 2.19 (0.83–3.81) | < 0.01 |
Fluid balance 72 h [Lt., M (IQR)] | 2.83 (0.27–5.18) | 6.28 (3.05–9.48) | 3.33 (0.89–6.42) | < 0.01 |
Packed red blood cells, first 24 h [U, M (IQR)] | 0 (0–3) | 2 (0–4) | 0 (0–4) | < 0.01 |
Number of patients requiring FFP transfusion [n(%)] | 52 (21.7) | 29 (38.7) | 23 (7.3%) | < 0.01 |
Administration of NaH2CO3 [n(%)] | 16 (6.7) | 11 (14.7) | 27 (8.6) | 0.03 |
Contrast administration [n(%)] | 149 (62.1) | 52 (69.3) | 201 (63.8) | 0.25 |
Contrast dose ×100 mg [M (IQR)] | 1.0 (0–1.5) | 1.0 (0–2.0) | 1 (0–2) | 0.15 |
Norephinephrine administration [n(%)] | 92 (38.3) | 45 (60.0) | 173 (54.9) | < 0.01 |
Vasopresina administration [n(%)] | 30 (12.5) | 14 (18.7) | 44 (14.0) | 0.18 |
Dobutamine administration [n(%)] | 9 (3.7) | 11 (14.7) | 20 (6.3) | < 0.01 |