Table 3 Demographic and clinicopathological variables compared according to the PLR and NLR values
Item | All (N = 292) | PLR ≤ 0.55 (n = 89) | PLR > 0.55 (n = 203) | P value+ | NLR ≤ 3.92 (n = 226) | NLR > 3.92 (n = 66) | P value+ |
|---|---|---|---|---|---|---|---|
Age (years, mean ± SD) | 61.1 ± 11.3 | 64.6 ± 11.0 | 59.6 ± 11.1 | < 0.001* | 60.3 ± 11.2 | 64 ± 11.2 | 0.033* |
Sex (Male) [n(%)] | 196 (67.1) | 65 (73.0) | 131 (64.5) | 0.156 | 147 (65.0) | 49 (74.2) | 0.163 |
AJCC stage | 0.013* | 0.004* | |||||
Stage 1[n(%)] | 70 (24.0) | 15 (16.9) | 55 (27.1) | 62 (27.4) | 8 (12.1) | ||
Stage 2[n(%)] | 82 (28.1) | 25 (28.1) | 57 (28.1) | 64 (28.3) | 18 (27.3) | ||
Stage 3[n(%)] | 107 (36.6) | 32 (36.0) | 75 (36.9) | 78 (34.5) | 29 (43.9) | ||
Stage 4[n(%)] | 33 (11.3) | 17 (19.1) | 16 (7.9) | 22 (9.7) | 11 (16.7) | ||
Tumor extent (size) | 0.002* | 0.001* | |||||
1[n(%)] | 62 (21.2) | 11 (12.4) | 51 (25.1) | 57 (25.2) | 5 (7.6) | ||
2[n(%)] | 40 (13.7) | 12 (13.5) | 28 (13.8) | 32 (14.2) | 8 (12.1) | ||
3[n(%)] | 164 (56.2) | 52 (58.4) | 112 (55.2) | 120 (53.1) | 44 (66.7) | ||
4[n(%)] | 26 (8.9) | 14 (15.7) | 12 (5.9) | 17 (7.5) | 9 (13.6) | ||
Lymph node count | 0.794 | 0.240 | |||||
0[n(%)] | 83 (28.4) | 24 (27.0) | 59 (29.1) | 68 (30.1) | 15 (22.7) | ||
1[n(%)] | 60 (20.5) | 18 (20.2) | 42 (20.7) | 48 (21.2) | 12 (18.2) | ||
2[n(%)] | 50 (17.1) | 17 (19.1) | 33 (16.3) | 35 (15.5) | 15 (22.7) | ||
3[n(%)] | 99 (33.9) | 30 (33.7) | 69 (34.0) | 75 (33.2) | 24 (36.4) | ||
Distant metastases [n(%)] | 33 (11.3) | 17 (19.1) | 16 (7.9) | 0.005* | 22(9.7) | 11 (16.7) | 0.118 |
Location of the tumor | 0.259 | 0.840 | |||||
Cardia/ fundus [n(%)] | 54 (18.5) | 24 (27.0) | 30 (14.8) | 39 (17.3) | 15 (22.7) | ||
Body [n(%)] | 194 (66.4) | 49 (55.1) | 145 (71.4) | 155 (68.6) | 39 (59.1) | ||
Antrum/ pylorus [n(%)] | 44 (15.1) | 16 (18.0) | 28 (13.8) | 32 (14.2) | 12 (18.2) | ||
Total gastrectomy [n(%)] | 152 (52.1) | 53(59.6) | 99 (48.8) | 0.090 | 116 (51.3) | 36 (54.5) | 0.647 |
Size of the tumor> 3 cm [n(%)] | 221 (75.7) | 71 (79.8) | 150 (73.9) | 0.282 | 166 (73.5) | 55 (83.3) | 0.100 |
Histological grade | 0.542 | 0.852 | |||||
Well differentiated [n(%)] | 71 (24.3) | 20 (22.5) | 51 (25.1) | 55 (24.3) | 16 (24.2) | ||
Moderately differentiated [n(%)] | 103 (35.3) | 36 (40.4) | 67 (33.0) | 81 (35.8) | 22 (33.3) | ||
Poorly differentiated [n(%)] | 77 (26.4) | 25 (28.1) | 52 (25.6) | 58 (25.7) | 19 (28.8) | ||
Signet ring [n(%)] | 41 (14.0) | 8 (9.0) | 33 (16.3) | 32 (14.2) | 9 (13.6) | ||
Lymphatic invasion [n(%)] | 211 (72.3) | 66 (74.2) | 145 (71.4) | 0.633 | 155 (68.6) | 56 (84.8) | 0.009* |
Perineural invasion [n(%)] | 161 (55.1) | 50 (56.2) | 111 (54.7) | 0.737 | 118 (52.2) | 43 (65.2) | 0.047* |
Vascular invasion [n(%)] | 170 (58.2) | 54 (60.7) | 116 (57.1) | 0.575 | 126 (55.8) | 44 (66.7) | 0.115 |