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Table 3 Demographic and clinicopathological variables compared according to the PLR and NLR values

From: Does the preoperative platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio predict morbidity after gastrectomy for gastric cancer?

Item All (N = 292) PLR ≤ 0.55 (n = 89) PLR > 0.55 (n = 203) P value+ NLR ≤ 3.92 (n = 226) NLR > 3.92 (n = 66) P value+
Age (years, mean ± SD) 61.1 ± 11.3 64.6 ± 11.0 59.6 ± 11.1 < 0.001* 60.3 ± 11.2 64 ± 11.2 0.033*
Sex (Male) [n(%)] 196 (67.1) 65 (73.0) 131 (64.5) 0.156 147 (65.0) 49 (74.2) 0.163
AJCC stage     0.013*    0.004*
 Stage 1[n(%)] 70 (24.0) 15 (16.9) 55 (27.1)   62 (27.4) 8 (12.1)  
 Stage 2[n(%)] 82 (28.1) 25 (28.1) 57 (28.1)   64 (28.3) 18 (27.3)  
 Stage 3[n(%)] 107 (36.6) 32 (36.0) 75 (36.9) 78 (34.5) 29 (43.9)  
 Stage 4[n(%)] 33 (11.3) 17 (19.1) 16 (7.9)   22 (9.7) 11 (16.7)  
Tumor extent (size)     0.002*    0.001*
 1[n(%)] 62 (21.2) 11 (12.4) 51 (25.1)   57 (25.2) 5 (7.6)  
 2[n(%)] 40 (13.7) 12 (13.5) 28 (13.8) 32 (14.2) 8 (12.1)  
 3[n(%)] 164 (56.2) 52 (58.4) 112 (55.2) 120 (53.1) 44 (66.7)  
 4[n(%)] 26 (8.9) 14 (15.7) 12 (5.9) 17 (7.5) 9 (13.6)  
Lymph node count     0.794    0.240
 0[n(%)] 83 (28.4) 24 (27.0) 59 (29.1)   68 (30.1) 15 (22.7)  
 1[n(%)] 60 (20.5) 18 (20.2) 42 (20.7) 48 (21.2) 12 (18.2)  
 2[n(%)] 50 (17.1) 17 (19.1) 33 (16.3) 35 (15.5) 15 (22.7)  
 3[n(%)] 99 (33.9) 30 (33.7) 69 (34.0) 75 (33.2) 24 (36.4)  
Distant metastases [n(%)] 33 (11.3) 17 (19.1) 16 (7.9) 0.005* 22(9.7) 11 (16.7) 0.118
Location of the tumor     0.259    0.840
 Cardia/ fundus [n(%)] 54 (18.5) 24 (27.0) 30 (14.8)   39 (17.3) 15 (22.7)  
 Body [n(%)] 194 (66.4) 49 (55.1) 145 (71.4) 155 (68.6) 39 (59.1)  
 Antrum/ pylorus [n(%)] 44 (15.1) 16 (18.0) 28 (13.8) 32 (14.2) 12 (18.2)  
Total gastrectomy [n(%)] 152 (52.1) 53(59.6) 99 (48.8) 0.090 116 (51.3) 36 (54.5) 0.647
Size of the tumor> 3 cm [n(%)] 221 (75.7) 71 (79.8) 150 (73.9) 0.282 166 (73.5) 55 (83.3) 0.100
Histological grade     0.542    0.852
 Well differentiated [n(%)] 71 (24.3) 20 (22.5) 51 (25.1)   55 (24.3) 16 (24.2)  
 Moderately differentiated [n(%)] 103 (35.3) 36 (40.4) 67 (33.0) 81 (35.8) 22 (33.3)  
 Poorly differentiated [n(%)] 77 (26.4) 25 (28.1) 52 (25.6) 58 (25.7) 19 (28.8)  
 Signet ring [n(%)] 41 (14.0) 8 (9.0) 33 (16.3) 32 (14.2) 9 (13.6)  
Lymphatic invasion [n(%)] 211 (72.3) 66 (74.2) 145 (71.4) 0.633 155 (68.6) 56 (84.8) 0.009*
Perineural invasion [n(%)] 161 (55.1) 50 (56.2) 111 (54.7) 0.737 118 (52.2) 43 (65.2) 0.047*
Vascular invasion [n(%)] 170 (58.2) 54 (60.7) 116 (57.1) 0.575 126 (55.8) 44 (66.7) 0.115
  1. P value+ were calculated for the comparison of groups based on the NLR and PLR values by statistical analysis; +Determined by the Mann-Whitney U test or Spearman’s rho test; *. P value < 0.05; AJCC American Joint Committee on Cancer, PLR platelet-to-lymphocyte ratio, NLR neutrophil-to-lymphocyte ratio