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Table 3 Demographic and clinicopathological variables compared according to the PLR and NLR values

From: Does the preoperative platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio predict morbidity after gastrectomy for gastric cancer?

ItemAll (N = 292)PLR ≤ 0.55 (n = 89)PLR > 0.55 (n = 203)P value+NLR ≤ 3.92 (n = 226)NLR > 3.92 (n = 66)P value+
Age (years, mean ± SD)61.1 ± 11.364.6 ± 11.059.6 ± 11.1< 0.001*60.3 ± 11.264 ± 11.20.033*
Sex (Male) [n(%)]196 (67.1)65 (73.0)131 (64.5)0.156147 (65.0)49 (74.2)0.163
AJCC stage   0.013*  0.004*
 Stage 1[n(%)]70 (24.0)15 (16.9)55 (27.1) 62 (27.4)8 (12.1) 
 Stage 2[n(%)]82 (28.1)25 (28.1)57 (28.1) 64 (28.3)18 (27.3) 
 Stage 3[n(%)]107 (36.6)32 (36.0)75 (36.9)78 (34.5)29 (43.9) 
 Stage 4[n(%)]33 (11.3)17 (19.1)16 (7.9) 22 (9.7)11 (16.7) 
Tumor extent (size)   0.002*  0.001*
 1[n(%)]62 (21.2)11 (12.4)51 (25.1) 57 (25.2)5 (7.6) 
 2[n(%)]40 (13.7)12 (13.5)28 (13.8)32 (14.2)8 (12.1) 
 3[n(%)]164 (56.2)52 (58.4)112 (55.2)120 (53.1)44 (66.7) 
 4[n(%)]26 (8.9)14 (15.7)12 (5.9)17 (7.5)9 (13.6) 
Lymph node count   0.794  0.240
 0[n(%)]83 (28.4)24 (27.0)59 (29.1) 68 (30.1)15 (22.7) 
 1[n(%)]60 (20.5)18 (20.2)42 (20.7)48 (21.2)12 (18.2) 
 2[n(%)]50 (17.1)17 (19.1)33 (16.3)35 (15.5)15 (22.7) 
 3[n(%)]99 (33.9)30 (33.7)69 (34.0)75 (33.2)24 (36.4) 
Distant metastases [n(%)]33 (11.3)17 (19.1)16 (7.9)0.005*22(9.7)11 (16.7)0.118
Location of the tumor   0.259  0.840
 Cardia/ fundus [n(%)]54 (18.5)24 (27.0)30 (14.8) 39 (17.3)15 (22.7) 
 Body [n(%)]194 (66.4)49 (55.1)145 (71.4)155 (68.6)39 (59.1) 
 Antrum/ pylorus [n(%)]44 (15.1)16 (18.0)28 (13.8)32 (14.2)12 (18.2) 
Total gastrectomy [n(%)]152 (52.1)53(59.6)99 (48.8)0.090116 (51.3)36 (54.5)0.647
Size of the tumor> 3 cm [n(%)]221 (75.7)71 (79.8)150 (73.9)0.282166 (73.5)55 (83.3)0.100
Histological grade   0.542  0.852
 Well differentiated [n(%)]71 (24.3)20 (22.5)51 (25.1) 55 (24.3)16 (24.2) 
 Moderately differentiated [n(%)]103 (35.3)36 (40.4)67 (33.0)81 (35.8)22 (33.3) 
 Poorly differentiated [n(%)]77 (26.4)25 (28.1)52 (25.6)58 (25.7)19 (28.8) 
 Signet ring [n(%)]41 (14.0)8 (9.0)33 (16.3)32 (14.2)9 (13.6) 
Lymphatic invasion [n(%)]211 (72.3)66 (74.2)145 (71.4)0.633155 (68.6)56 (84.8)0.009*
Perineural invasion [n(%)]161 (55.1)50 (56.2)111 (54.7)0.737118 (52.2)43 (65.2)0.047*
Vascular invasion [n(%)]170 (58.2)54 (60.7)116 (57.1)0.575126 (55.8)44 (66.7)0.115
  1. P value+ were calculated for the comparison of groups based on the NLR and PLR values by statistical analysis; +Determined by the Mann-Whitney U test or Spearman’s rho test; *. P value < 0.05; AJCC American Joint Committee on Cancer, PLR platelet-to-lymphocyte ratio, NLR neutrophil-to-lymphocyte ratio