|
Age (years, mean ± SD)
|
61.1 ± 11.3
|
64.6 ± 11.0
|
59.6 ± 11.1
|
< 0.001*
|
60.3 ± 11.2
|
64 ± 11.2
|
0.033*
|
|
Sex (Male) [n(%)]
|
196 (67.1)
|
65 (73.0)
|
131 (64.5)
|
0.156
|
147 (65.0)
|
49 (74.2)
|
0.163
|
|
AJCC stage
| | | |
0.013*
| | |
0.004*
|
|
Stage 1[n(%)]
|
70 (24.0)
|
15 (16.9)
|
55 (27.1)
| |
62 (27.4)
|
8 (12.1)
| |
|
Stage 2[n(%)]
|
82 (28.1)
|
25 (28.1)
|
57 (28.1)
| |
64 (28.3)
|
18 (27.3)
| |
|
Stage 3[n(%)]
|
107 (36.6)
|
32 (36.0)
|
75 (36.9)
|
78 (34.5)
|
29 (43.9)
| |
|
Stage 4[n(%)]
|
33 (11.3)
|
17 (19.1)
|
16 (7.9)
| |
22 (9.7)
|
11 (16.7)
| |
|
Tumor extent (size)
| | | |
0.002*
| | |
0.001*
|
|
1[n(%)]
|
62 (21.2)
|
11 (12.4)
|
51 (25.1)
| |
57 (25.2)
|
5 (7.6)
| |
|
2[n(%)]
|
40 (13.7)
|
12 (13.5)
|
28 (13.8)
|
32 (14.2)
|
8 (12.1)
| |
|
3[n(%)]
|
164 (56.2)
|
52 (58.4)
|
112 (55.2)
|
120 (53.1)
|
44 (66.7)
| |
|
4[n(%)]
|
26 (8.9)
|
14 (15.7)
|
12 (5.9)
|
17 (7.5)
|
9 (13.6)
| |
|
Lymph node count
| | | |
0.794
| | |
0.240
|
|
0[n(%)]
|
83 (28.4)
|
24 (27.0)
|
59 (29.1)
| |
68 (30.1)
|
15 (22.7)
| |
|
1[n(%)]
|
60 (20.5)
|
18 (20.2)
|
42 (20.7)
|
48 (21.2)
|
12 (18.2)
| |
|
2[n(%)]
|
50 (17.1)
|
17 (19.1)
|
33 (16.3)
|
35 (15.5)
|
15 (22.7)
| |
|
3[n(%)]
|
99 (33.9)
|
30 (33.7)
|
69 (34.0)
|
75 (33.2)
|
24 (36.4)
| |
|
Distant metastases [n(%)]
|
33 (11.3)
|
17 (19.1)
|
16 (7.9)
|
0.005*
|
22(9.7)
|
11 (16.7)
|
0.118
|
|
Location of the tumor
| | | |
0.259
| | |
0.840
|
|
Cardia/ fundus [n(%)]
|
54 (18.5)
|
24 (27.0)
|
30 (14.8)
| |
39 (17.3)
|
15 (22.7)
| |
|
Body [n(%)]
|
194 (66.4)
|
49 (55.1)
|
145 (71.4)
|
155 (68.6)
|
39 (59.1)
| |
|
Antrum/ pylorus [n(%)]
|
44 (15.1)
|
16 (18.0)
|
28 (13.8)
|
32 (14.2)
|
12 (18.2)
| |
|
Total gastrectomy [n(%)]
|
152 (52.1)
|
53(59.6)
|
99 (48.8)
|
0.090
|
116 (51.3)
|
36 (54.5)
|
0.647
|
|
Size of the tumor> 3 cm [n(%)]
|
221 (75.7)
|
71 (79.8)
|
150 (73.9)
|
0.282
|
166 (73.5)
|
55 (83.3)
|
0.100
|
|
Histological grade
| | | |
0.542
| | |
0.852
|
|
Well differentiated [n(%)]
|
71 (24.3)
|
20 (22.5)
|
51 (25.1)
| |
55 (24.3)
|
16 (24.2)
| |
|
Moderately differentiated [n(%)]
|
103 (35.3)
|
36 (40.4)
|
67 (33.0)
|
81 (35.8)
|
22 (33.3)
| |
|
Poorly differentiated [n(%)]
|
77 (26.4)
|
25 (28.1)
|
52 (25.6)
|
58 (25.7)
|
19 (28.8)
| |
|
Signet ring [n(%)]
|
41 (14.0)
|
8 (9.0)
|
33 (16.3)
|
32 (14.2)
|
9 (13.6)
| |
|
Lymphatic invasion [n(%)]
|
211 (72.3)
|
66 (74.2)
|
145 (71.4)
|
0.633
|
155 (68.6)
|
56 (84.8)
|
0.009*
|
|
Perineural invasion [n(%)]
|
161 (55.1)
|
50 (56.2)
|
111 (54.7)
|
0.737
|
118 (52.2)
|
43 (65.2)
|
0.047*
|
|
Vascular invasion [n(%)]
|
170 (58.2)
|
54 (60.7)
|
116 (57.1)
|
0.575
|
126 (55.8)
|
44 (66.7)
|
0.115
|
