Skip to main content

Advertisement

Table 1 Blood eosinophilia classification, modified from Valent et al. [5]

From: A diagnostic protocol designed for determining allergic causes in patients with blood eosinophilia

Classification Definition
Secondary reactive eosinophilia Underlying condition/disease in which eosinophils are considered non-clonal cells; eosinophilia considered cytokine driven in most cases
Primary neoplastic eosinophilia Underlying stem cell, myeloid, or eosinophilic neoplasm, as classified by WHO criteria; eosinophils considered neoplastic cells
Hereditary eosinophilia Pathogenesis unknown; familial clustering, no signs or symptoms of hereditary immunodeficiency, and no evidence of a reactive or neoplastic condition/disorder underlying eosinophilia
HE of undetermined significance No underlying cause of eosinophilia, no family history, no evidence of a reactive or neoplastic condition/disorder underlying eosinophilia, and no end-organ damage attributable to eosinophilia