A specific objective supplemental factor in evaluating acute mountain sickness: ΔHR in combination with SaO2

Table 4 The assessment test with the cutoff of △HR or SaO₂ for AMS

Cutoff		AMS	Non-AMS	N	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
AEG
SaO₂ < 88 %	Yes	160	68	228	0.35	0.77	0.70	0.43
SaO₂ < 88 %	No	301	223	524	0.35	0.77	0.70	0.43
△HR > 25	Yes	155	52	207	0.34	0.82	0.75	0.44
△HR > 25	No	306	239	545	0.34	0.82	0.75	0.44
SaO₂ < 88 % + △HR >25	Yes	73	9	82	0.16	0.97	0.89	0.42
SaO₂ < 88 % + △HR >25	No	388	282	670	0.16	0.97	0.89	0.42
PAG
SaO₂ < 86 %	Yes	33	27	60	0.32	0.83	0.55	0.66
SaO₂ < 86 %	No	71	136	207	0.32	0.83	0.55	0.66
△HR > 15	Yes	37	29	66	0.36	0.82	0.56	0.67
△HR > 15	No	67	134	201	0.36	0.82	0.56	0.67
SaO₂ < 86 % + △HR > 15	Yes	17	3	20	0.16	0.98	0.85	0.65
SaO₂ < 86 % + △HR > 15	No	87	160	247	0.16	0.98	0.85	0.65

AEG Acute exposure group, PAG Pre-acclimatization group, △ HR The difference of HR between pre-exposure and post-exposure, PPV Positive predictive value, NPV Negative predictive value

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