|
Source
|
Number of patients
|
Mean age (years)
|
Male (%)
|
Center
|
Mean APACHE II/SAPS II/SOFA score
|
Blood pressure (mmHg)
|
|---|
|
Russell JA, 2013 [12]
|
394
|
62.8
|
233 (59.1)
|
M
|
26.8/NR/NR
|
MAP <65
|
|
Daley MJ, 2013 [7]
|
130
|
58.5
|
69 (53.1)
|
S
|
27.8/NR/NR
|
MAP <65
|
|
Gordon AC, 2010 [13]
|
778
|
61.8
|
475 (61.0)
|
M
|
27.1/NR/NR
|
MAP 72.7 (NE maintenance)
|
|
Russell JA, 2009 [14]
|
190
|
61
|
116 (61.1)
|
M
|
26.5/NR/NR
|
MAP <60
|
|
Morelli A, 2009 [15]
|
45
|
65.7
|
33 (73.3)
|
S
|
NR/60/NR
|
MAP <65
|
|
Russell JA, 2008 [8]
|
778
|
60.6
|
475 (61.1)
|
M
|
27.1/NR/NR
|
MAP 72.5 (vasopressor maintenance)
|
|
Lauzier F, 2006 [16]
|
23
|
54.7
|
14 (60.9)
|
M
|
23.2/NR/8.9
|
MAP <60
|
- APACHE, acute physiology and chronic health evaluation; SAPS, simplified acute physiology score; SOFA, sequential organ failure assessment; MAP, mean arterial pressure; S, single-center trial; M, multicenter trial; NE, norepinephrine; NR, not reported.
