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Table 2 Applications of radiomics-based tumor staging

From: Artificial intelligence-driven radiomics study in cancer: the role of feature engineering and modeling

Image modality

Number of patients

Cancer

Target

Number of radiomics features

Commercial or open-source software

Method

References

MRI

127

HNSCC

Preoperative staging (stage I–II from stage III–IV)

6

ITK-SNAP, Matlab, R, SPSS

ML: LASSO, LR

SM: Mann–Whitney U test, McNemar test

[17]

CT

154

Esophageal cancer

Preoperative staging

10

Matlab, R

ML: LASSO, fivefold CV

SM: Mann–Whitney U test, DeLong test, Net reclassification improvement, Chi-square test, ICC

[18]

CT

494

Primary colorectal cancer

Preoperative staging

16

Matkab, SPSS

ML: LASSO, LR

SM: Mann–Whitney U test, DeLong test

[19]

US

157

Bladder cancer

Tumor staging

30

ITK-SNAP, Intelligence Foundry, SPSS

ML: SVM-RFE, L1-regularized LR, Random forests, DT, Naive Bayes, KNN, Bagging, Extremely RF, AdaBoost, Gradient

boosting regression trees, fivefold CV

SM: t-test, Chi-square test, Z-score, Spearman correlation analysis, Mann–Whitney U test

[20]

  1. MRI magnetic resonance imaging, CT computed tomography, US ultrasonography, ML machine learning, SM statistical method, HNSCC head and neck squamous cell carcinoma, LASSO least absolute shrinkage and selection operator, LR logistic regression, CV cross validation, ICC intraclass correlation coefficients, SVM support vector machine, RFE recursive feature elimination, DT decision tree, KNN K-nearest neighbors, RF random forest, AdaBoost adaptive boosting