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Fig. 1 | Military Medical Research

Fig. 1

From: Recent advances in CRISPR-based genome editing technology and its applications in cardiovascular research

Fig. 1

Characteristics of novel Cas orthologs and engineered variants. a Representative type I Cas orthologs capable of large-range deletions. b Representative Cas orthologs of miniature sizes. c Engineered Cas variants with diverse protospacer adjacent motif recognition capabilities. d Structure-guided strategies for improving DNA specificity without affecting the on-target cleavage efficiency

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Military Medical Research

ISSN: 2054-9369