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Fig. 2 | Military Medical Research

Fig. 2

From: The role of the immune microenvironment in bone, cartilage, and soft tissue regeneration: from mechanism to therapeutic opportunity

Fig. 2

The important roles of T cells in the regulation of tissue regeneration. a Tregs modulate the activity of many other types of stem and progenitor cells involved in regeneration, and have become a crucial cell type for tissue repair and regeneration. b γδ T cells promote tissue repair and regeneration through communication with tissue stem cells. c CD4 T cells enhance tissue regeneration through the regulation of macrophages and fibroblasts, and CD8 T cells impair bone remodeling by hindering MSC proliferation and differentiation. MSCs mesenchymal stem cells

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