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Table 2 EVs in the diagnosis of ALI/ARDS

From: Extracellular vesicles in the pathogenesis and treatment of acute lung injury

EVs source

Molecules

Prediction

References

Plasma

miR-34a, miR-15a and miR-27a

Shock

[106]

Serum

miR-126, miR-27a, miR-146a and miR-155

Severe community-acquired pneumonia-ARDS

[107]

Serum

miR-145

Sepsis

[108]

Alveolar macrophages

TNF and IL-10 protein

LPS-ALI

[109]

BALF

TNF, IL-1β/IL-6

LPS-ALI

[110]

BALF

Mitochondrial material

Streptococcus pneumonia infection

[111]

  1. EVs extracellular vesicles, ALI acute lung injury, ARDS acute respiratory distress syndrome, BALF bronchoalveolar lavage fluid, IL interleukin, TNF tumor necrosis factor, LPS lipopolysaccharide