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Fig. 2 | Military Medical Research

Fig. 2

From: Recent developments in application of single-cell RNA sequencing in the tumour immune microenvironment and cancer therapy

Fig. 2

New resolution of immune cell clusters revealed by scRNA-seq. With the help of scRNA-seq, novel cell clusters of CAFs, T cells, TAMs and DCs have been identified. CAFs cancer-associated fibroblasts, cCAFs cycling CAFs, dCAFs developmental CAFs, apCAFs antigen-presenting CAFs, iCAFs inflammatory CAFs, myCAFs myofibroblastic CAFs, mCAFs matrix CAFs, TAMs tumour-associated macrophages, DCs dendritic cells, cDC conventional DC, FCN1 ficolin 1, LAMP3 lysosomal associated membrane protein 3, SPP1 secreted phosphoprotein 1, FOLR2 folate receptor Beta, Tregs regulatory T cells, NK natural killer, CSG cell surface glycoprotein, GZMK granzyme K, CXCL13 C-X-C motif chemokine ligand 13, BHLHE40 basic helix-loop-helix family member E40, Th1 T helper 1, KIR killer cell immunoglobulin like receptor, LAYN layilin, TCF7 transcription factor 7, LAG3 lymphocyte activating 3

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