Table 1 Detailed drug concentrations and the calculated IC50 values of each treatment (drug concentration unit: µmol/L)
Treatments | Channel number | Calculated IC50 | ||||||
|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | |||
K562 cell line | ||||||||
SC | Ima | 0 | 0.63 | 1.26 | 1.89 | 2.52 | 3.00 | 1.57 |
Res | 0 | 63.21 | 126.18 | 189.15 | 252.12 | 300.00 | 97.15 | |
Ima/Res | 0 | 0.42/31.61 | 0.84/63.09 | 1.26/94.58 | 1.68/126.06 | 2/150 | 0.60/45.00 | |
SCDC | Ima | 0 | 2.95 | 5.89 | 8.83 | 11.77 | 14.00 | 2.99 |
Res | 0 | 105.35 | 210.30 | 315.25 | 420.20 | 500.00 | 90.03 | |
Ima/Res | 0 | 1.69/52.68 | 3.36/105.15 | 5.04/157.63 | 6.72/210.10 | 8/250 | 1.58/49.38 | |
AML primary cell | ||||||||
P1 | Ara-C/DNR | 0 | 2.11/0.42 | 4.21/0.84 | 6.31/1.26 | 8.40/1.68 | 10.0/2.0 | 1.75/0.35 |
P2 | Ara-C/DNR | 0 | 2.11/0.42 | 4.21/0.84 | 6.31/1.26 | 8.40/1.68 | 10.0/2.0 | 4.25/0.85 |