Skip to main content
Fig. 7 | Military Medical Research

Fig. 7

From: Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles

Fig. 7

C3 and C4 affect osteoclast differentiation dependent on suppressing histone deacetylase. a Representative images of TRAP-positive multi-nucleated (≥ 5 nuclei) osteoclasts. b Representative immunofluorescence co-immunostaining images of osteoclasts stained with TRAF2 (green), NFATc-1 (red), and DAPI (blue). c Relative expression of osteoclast-related proteins. C3 propionate, C4 butyrate, IL-1β interleukin 1 beta, TSA trichostatin A, TRAP tartrate resistant acid phosphatase, NFATc-1 nuclear factor of activated T-cells, cytoplasmic 1, MMP9 matrix metalloprotein 9, CTSK cathepsin K

Back to article page

Military Medical Research

ISSN: 2054-9369