Fig. 4From: Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSADocking simulation of CQ binding to PfLDH, PfOAT, PfPyrK, PfPGK and PfTPI proteins, respectively. The calculated binding affinities (kcal/mol) are -6.2, -6.1, -6.5, -5.7 and -5.8 for PfLDH, PfOAT, PfPyrK, PfPGK and PfTPI, respectively. Pf Plasmodium falciparum, LDH L-lactate dehydrogenase, OAT ornithine aminotransferase, PyrK pyruvate kinase, PGK phosphoglycerate kinase, TPI triosephosphate isomeraseBack to article page