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Fig. 3 | Military Medical Research

Fig. 3

From: Down-regulation of Risa improves podocyte injury by enhancing autophagy in diabetic nephropathy

Fig. 3

Effect of Risa overexpression and Risa inhibition on HG-induced podocyte autophagy damage. The level of LC3B was detected by Western blotting (a) and immunofluorescence (b) in the mouse groups and MPC groups. The bar graph shows the quantification of LC3B II/I. c Level of NPHS2 was detected by Western blotting. Values are expressed as mean ± SD of three independent experiments. ***P < 0.001 vs. db/m group, ###P < 0.001 vs. db/db group or HG and HG + Risa-vehicle groups. MPCs mouse podocyte cells, Risa lncRNA AK044604, AAV adeno-associated virus, GAPDH glyceraldehyde-3-phosphate dehydrogenase, HG high glucose

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