Fig. 1From: Multimodal therapy strategies based on hydrogels for the repair of spinal cord injuryMechanisms of spinal cord injury (SCI) and different models therapy based on hydrogels. a A range of pathologic mechanisms following SCI: primary injury including demyelination and cyst formation. Secondary injury including loss of neurons/axons, inflammation and glial scar. b Multimodal therapy strategies based on hydrogel: injectable hydrogels therapy, tissue engineering and combination therapy. The therapy mechanisms based on hydrogels: promote new neurons formation, promote axonal growth, remove inflammatory cells and factors, eliminate cyst, inhibit glial scar formation, promote axonal regeneration. ECM extracellular matrixBack to article page