Skip to main content

Table 3 Multivariate analysis of clinicopathological characteristics for the Chinese dataset

From: Standardizing the classification of gastric cancer patients with limited and adequate number of retrieved lymph nodes: an externally validated approach using real-world data

Model 1*

Model 2†

Characteristics

HR

95% CI

P value

Characteristics

HR

95% CI

P value

Age (years)

       

 ≤ 60

Ref

   

Ref

  

 > 60

1.344

1.254–1.440

 < 0.001

 

1.342

1.252–1.437

 < 0.001

Tumor size (cm)

       

 ≤ 4.5

Ref

   

Ref

  

 > 4.5

1.252

1.164–1.347

 < 0.001

 

1.254

1.166–1.348

 < 0.001

Tumor location

       

 Lower 1/3

Ref

   

Ref

  

 Middle 1/3

1.216

1.106–1.336

 < 0.001

 

1.214

1.105–1.335

 < 0.001

 Upper 1/3

1.132

1.039–1.234

0.005

 

1.126

1.034–1.227

0.006

 Entire stomach

1.575

1.404–1.767

 < 0.001

 

1.561

1.392–1.750

 < 0.001

Lauren type

       

 Intestinal

Ref

   

Ref

  

 Diffuse

1.162

1.081–1.249

 < 0.001

 

1.160

1.079–1.247

 < 0.001

Total LNs retrieval

       

 ≥ 16

Ref

   

Ref

  

 < 16

1.583

1.463–1.712

 < 0.001

 

0.997

0.924–1.075

0.940

pT

       

 T1

Ref

   

Ref

  

 T2

4.329

3.225–5.810

 < 0.001

 

3.785

2.807–5.104

 < 0.001

 T3

4.943

3.676–6.645

 < 0.001

 

4.337

3.210–5.860

 < 0.001

 T4a

6.096

4.568–8.136

 < 0.001

 

5.345

3.985–7.171

 < 0.001

 T4b

8.144

5.994–11.066

 < 0.001

 

7.143

5.234–9.749

 < 0.001

pN

   

N’

   

 N0

Ref

  

 N0

Ref

  

 N1

1.853

1.645–2.087

 < 0.001

 N1

1.738

1.493–2.024

 < 0.001

 N2

2.530

2.264–2.827

 < 0.001

 N2

2.752

2.383–3.183

 < 0.001

 N3a

4.325

3.865–4.839

 < 0.001

 N3a

4.264

3.706–4.907

 < 0.001

 N3b

6.376

5.586–7.278

 < 0.001

 N3b

6.573

5.673–7.616

 < 0.001

  1. *Multivariate analysis Model 1: Clinicopathological factors including the 8th AJCC N classification. †Multivariate analysis Model 2: Clinicopathological factors including our proposed N’ classification. HR hazard ratio, CI confidence interval, Ref the corresponding variable subgroup which was used as reference when performing the multivariate analysis, T tumor size, LN lymph node, pT or pN pathological tumor or nodal classification, N’ modified nodal classification, NS non-significant, AJCC American Joint Commission on Cancer
Back to article page

Military Medical Research

ISSN: 2054-9369