Wave-shaped microfluidic chip assisted point-of-care testing for accurate and rapid diagnosis of infections

Table 1 Comparison of WMC-MDP detection capabilities

Detection method	WMC-MDP	CL [40]	Colorimetric	Fluorescence [41]	ECL [42]
Multiplex detecting	Y	Y	N	Y	N
Detection time (min)	22	70	90	33	> 240
Cost	Low	Medium	High	High	Medium
Performance of operations	Simple	Simple	Complicated	Simple	Complicated
LOD
CRP (μg/ml)	0.54	1.87	1.19	5.53	/
PCT (ng/ml)	0.11	0.17	0.15	/	/
IL-6 (pg/ml)	16.25	49.75	12.5	4.41	1

WMC-MDP wave-shaped microfluidic chip assisted multiplexed detection platform, CL chemiluminescence, ECL electro-chemiluminescence, Y yes, N no, LOD limit of detection, CRP c-reactive protein, PCT procalcitonin, IL-6 interleukin-6

ISSN: 2054-9369