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Fig. 2 | Military Medical Research

Fig. 2

From: Excellent effects and possible mechanisms of action of a new antibody–drug conjugate against EGFR-positive triple-negative breast cancer

Fig. 2

Effects of LR004-VC-MMAE on proliferation and colony formation of TNBC cells. a Effect of LR004-VC-MMAE on MDA-MB-468 and MDA-MB-231 cells viability. CCK-8 assays were used to assess the viability of cells treated with LR004-VC-MMAE for 48 or 72 h. b IC50 values of MDA-MB-468 and MDA-MB-231 cells. Cells were treated with LR004-VC-MMAE or MMAE for 72 h. The data are presented as the mean ± SD. c Colony forming ability of MDA-MB-468 and MDA-MB-231 cells. Representative images and colony counts (% of control) are shown. Data are presented as the mean ± SD. **P < 0.01, ***P < 0.001 vs. control. TNBC triple-negative breast cancer

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Military Medical Research

ISSN: 2054-9369