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Fig. 8 | Military Medical Research

Fig. 8

From: Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood–brain barrier injury through the Wnt/β-catenin signalling pathway

Fig. 8

Effects of combined silencing of the β-catenin and LMP2 genes on the expression of occludin, claudin-1 and ZO-1 proteins in RBMVECs following OGD/R. Western blotting and quantitative analysis of the expressions of occludin, claudin-1and ZO-1proteins in RBMVECs in each group. Data are presented as the mean ± standard deviation (SD) from three independent experiments. *P < 0.001, compared with the normal group; #P < 0.001, compared with the LMP2-siRNA group. OGD/R oxygen–glucose deprivation and reoxygenation. RBMVECs rat brain microvascular endothelial cells

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