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Fig. 6 | Military Medical Research

Fig. 6

From: Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood–brain barrier injury through the Wnt/β-catenin signalling pathway

Fig. 6

Silencing LMP2 decreased the expression of apoptosis-related proteins and promoted the proliferation and migration of RBMVECs following OGD/R. a Western blotting and quantitative analysis the levels of Bcl-2, Bax and cleaved caspase3-p17 proteins in RBMVECs in each group. b Cell scratch test showed that proliferation and migration repair ability of RBMVECs in each group. Scale bars = 250 µm. Data are presented as the mean ± standard deviation (SD) from three independent experiments. *P < 0.001, compared with the normal group; #P < 0.001, compared with the control-siRNA group. OGD/R oxygen–glucose deprivation and reoxygenation; RBMVECs rat brain microvascular endothelial cells

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Military Medical Research

ISSN: 2054-9369