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Table 3 The association between oxygen therapy and all-cause in-hospital mortality in subgroup analysis

From: Is oxygen therapy beneficial for normoxemic patients with acute heart failure? A propensity score matched study

Characteristics No. of total No. Ambient Air
(No. of deaths)
No. Oxygen Therapy
(No. of deaths)
OR (95% CI) P value
Duration of oxygen therapy (days)
  ≤ 3 741 741 (40) 0.87 (0.60–1.27) 0.472
 3–6 322 322 (28) 1.45 (0.94–2.25) 0.092
  > 6 167 167 (30) 3.34 (2.15–5.20) <  0.001
Median SpO2 during treatment period (%)
 90–95 753 431 (33) 322 (26) 1.06 (0.62–1.81) 0.832
  > 95 2169 1261 (71) 908 (72) 1.44 (1.03–2.03) 0.034
Age (years)
  ≤ 72 1498 856 (41) 642 (38) 1.25 (0.79–1.97) 0.334
  > 72 1424 836 (63) 588 (60) 1.39 (0.96–2.02) 0.079
de novo AHF (n)
 Yes 1155 659 (58) 496 (58) 1.37 (0.92–2.22) 0.111
 No 1767 1033 (46) 734 (40) 1.24 (0.85–1.82) 0.258
AF (n)
 Yes 668 381 (28) 287 (34) 1.69 (1.00–2.87) 0.049
 No 2254 1311 (76) 943 (64) 1.18 (0.84–1.67) 0.337
MI (n)
 Yes 561 331 (33) 230 (22) 0.96 (0.54–1.69) 0.874
 No 2361 1361 (71) 1000 (76) 1.49 (1.07–2.09) 0.019
Stroke (n)
 Yes 301 178 (14) 123 (17) 1.88 (0.89–3.97) 0.099
 No 2621 1514 (90) 1107 (81) 1.25 (0.92–1.70) 0.161
Hypertension (n)
 Yes 1869 1041 (61) 828 (59) 1.23 (0.85–1.79) 0.268
 No 1053 651 (43) 402 (39) 1.52 (0.97–2.39) 0.070
CKD (n)
 Yes 775 451 (40) 324 (36) 1.28 (0.80–2.07) 0302
 No 2147 1241 (64) 906 (62) 1.35 (0.94–1.94) 0.102
RRT (n)
 Yes 149 102 (4) 47 (6) 3.59 (0.96–13.38) 0.057
 No 2773 1590 (100) 1183 (92) 1.26 (0.94–1.69) 0.128
  1. OR odds ratio, CI confidence interval, SpO2 pulse oximetry-derived oxygen saturation, AHF acute heart failure, AF atrial fibrillation, MI myocardial infarction, CKD chronic kidney disease, RRT renal replacement treatment, no data