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Table 1 Baseline characteristics of the study patients according to the 3 subgroups with different fluid balance trajectory patterns

From: Association of fluid balance trajectories with clinical outcomes in patients with septic shock: a prospective multicenter cohort study

Characteristics

All (n = 986)

Fluid balance trajectory patterns

P

Decreasing FB

(n = 64)

Low FB

(n = 841)

High FB

(n = 81)

Fluid overload

198 (20.1)

33 (51.6)

87 (10.3) §

78 (96.3)§

<  0.001

Age (year, \( \overline{x} \) ± s)

63.7 ± 17.5

66.3 ± 18.9

63.3 ± 17.3

65.3 ± 18.6

0.292

Sex [male, n (%)]

624 (63.3)

37 (57.8)

535 (63.6)

52 (64.2)

0.640

APACHE II (\( \overline{x} \) ± s)

22.1 ± 7.8

24.7 ± 7.4

21.6 ± 7.8§

25.4 ± 7.4

<  0.001

SOFA [M (IQR)]

8.0 (6.0–11.0)

11.0 (8.0–13.0)

8.0 (5.0–10.0)§

10.5 (8.0–13.0)§

<  0.001

Source of admission [n (%)]

0.006

 Emergency department

175 (17.7)

12 (18.8)

143 (17.0)

20 (24.7)

 

 Medical

659 (66.8)

33 (51.6)

575 (68.4)§

51 (63.0)§

 

 Surgical

152 (15.4)

19 (29.7)

123 (14.6)§

10 (12.3)§

 

Comorbidities [n (%)]

 Respiratory disease

76 (7.7)

5 (7.8)

64 (7.6)

7 (8.6)

0.946

 Cardiovascular disease

155 (15.7)

11 (17.2)

130 (15.5)

14 (17.3)

0.862

 Hypertension

326 (33.1)

19 (29.7)

284 (33.4)

23 (28.4)

0.518

 Diabetes mellitus

192 (19.5)

9 (14.1)

167 (19.9)

16 (19.8)

0.528

 Cancer

117 (11.9)

11 (17.2)

92 (10.9)

14 (17.3)

0.096

 None

189 (19.2)

24 (37.5)

146 (17.7)§

19 (23.5)§

<  0.001

Treatments [n (%)]

 MV

826 (83.8)

62 (96.9)

691 (82.2)§

73 (90.1)§

0.002

 Renal replacement therapy

229 (23.2)

12 (18.8)

178 (21.2)

39 (48.1)§

<  0.001

  1. FB fluid balance, SD standard deviation, IQR interquartile range, APACHE II acute physiology and chronic health evaluation II, SOFA sequential organ failure assessment, MV mechanical ventilation, §Compared with decreasing FB, P <  0.05