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Fig. 4 | Military Medical Research

Fig. 4

From: Re-expression of DIRAS3 and p53 induces apoptosis and impaired autophagy in head and neck squamous cell carcinoma

Fig. 4

DIRAS3 and p53 re-expression inhibits the expression of multiple oncogenes in HNSCC cells. a. CAL-27 cells were treated with Ad-DIRAS3, rAd-p53, and their combination for 24 h. Ad-GFP was used as a negative control. The expression of c-Myc, cyclin D1, VEGF, FGF, EGFR and Bcl-2 proteins was determined by western blotting. b. Relative mRNA levels of c-Myc, cyclin D1, VEGF, FGF, EGFR and Bcl-2 were examined by real-time PCR. **P < 0.01; ***P < 0.001

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