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Table 4 Clinical management comparison by group

From: The impacts of infectious complications on outcomes in acute pancreatitis: a retrospective study

 

Sterile group (n = 148)

Pancreatic infection group (n = 65)

Extrapancreatic infection group (n = 22)

Combined infection group (n = 50)

Total (n = 285)

P*

Nutritional support [n(%)]

 Parenteral nutrition only

89(60.1)bd

17(26.2)a

8(36.4)

6 (12)a

120(42.1)

< 0.001

 Enteral and parenteral nutrition

53(35.8)bd

43(66.2)a

14(63.6)

41(82.0)a

151(53.0)

< 0.001

Antibiotics duration [d, mean ± SD]

9.53 ± 6.04bd

22.34 ± 13.56ad

17.32 ± 20.12d

40.32 ± 32.06abc

18.46 ± 19.92

< 0.001

Mechanical ventilation[n(%)]

29(19.6)cd

18(27.7)cd

12(54.5)ab

25(50.0)ab

84(29.5)

< 0.001

Extent of necrosis[n(%)]

  < 30%

99(66.9)bd

15(23.1)ac

14(63.6)bd

10(20)ac

138(48.4)

< 0.001

 30-50%

31(20.9)

23(35.4)

5(22.7)

16(32)

75(26.3)

 

  > 50%

18(12.2)

27(41.5)

3(13.7)

24(48)

72(25.3)

 

Surgical intervention(times/case)

 PCD

0.97 ± 0.84bd

1.95 ± 1.37ac

0.86 ± 1.04bd

2.38 ± 1.74ac

1.44 ± 1.32

< 0.001

 Surgical debridement*

0.07 ± 0.57bd

0.83 ± 1.34ac

0.18 ± 0.85bd

1.14 ± 1.97ac

0.44 ± 1.22

< 0.001

  1. PCD Percutaneous catheter drainage. *Surgical debridement: Including minimal access retroperitoneal pancreatic necrosectomy (MARPN), small incision pancreatic necrosectom (SIPN), or single-incision access port retroperitoneoscopic debridement (SIAPRD)
  2. * P value is the statistical value of ANOVA
  3. a Significant difference compared with the sterile group; b significant difference compared with the pancreatic infection group; c significant difference compared with the extrapancreatic infection group; d significant difference compared with the combined infection group, P <0.05 represents a statistically significant difference