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Table 4 Clinical management comparison by group

From: The impacts of infectious complications on outcomes in acute pancreatitis: a retrospective study

  Sterile group (n = 148) Pancreatic infection group (n = 65) Extrapancreatic infection group (n = 22) Combined infection group (n = 50) Total (n = 285) P*
Nutritional support [n(%)]
 Parenteral nutrition only 89(60.1)bd 17(26.2)a 8(36.4) 6 (12)a 120(42.1) < 0.001
 Enteral and parenteral nutrition 53(35.8)bd 43(66.2)a 14(63.6) 41(82.0)a 151(53.0) < 0.001
Antibiotics duration [d, mean ± SD] 9.53 ± 6.04bd 22.34 ± 13.56ad 17.32 ± 20.12d 40.32 ± 32.06abc 18.46 ± 19.92 < 0.001
Mechanical ventilation[n(%)] 29(19.6)cd 18(27.7)cd 12(54.5)ab 25(50.0)ab 84(29.5) < 0.001
Extent of necrosis[n(%)]
  < 30% 99(66.9)bd 15(23.1)ac 14(63.6)bd 10(20)ac 138(48.4) < 0.001
 30-50% 31(20.9) 23(35.4) 5(22.7) 16(32) 75(26.3)  
  > 50% 18(12.2) 27(41.5) 3(13.7) 24(48) 72(25.3)  
Surgical intervention(times/case)
 PCD 0.97 ± 0.84bd 1.95 ± 1.37ac 0.86 ± 1.04bd 2.38 ± 1.74ac 1.44 ± 1.32 < 0.001
 Surgical debridement* 0.07 ± 0.57bd 0.83 ± 1.34ac 0.18 ± 0.85bd 1.14 ± 1.97ac 0.44 ± 1.22 < 0.001
  1. PCD Percutaneous catheter drainage. *Surgical debridement: Including minimal access retroperitoneal pancreatic necrosectomy (MARPN), small incision pancreatic necrosectom (SIPN), or single-incision access port retroperitoneoscopic debridement (SIAPRD)
  2. * P value is the statistical value of ANOVA
  3. a Significant difference compared with the sterile group; b significant difference compared with the pancreatic infection group; c significant difference compared with the extrapancreatic infection group; d significant difference compared with the combined infection group, P <0.05 represents a statistically significant difference