Table 2 Liver function of the patients with COVID-19 during hospitalization [n (%)].
From: Pattern of liver injury in adult patients with COVID-19: a retrospective analysis of 105 patients
Item | Overall | Mild group | Severe group | P-value |
|---|---|---|---|---|
ALT | (n = 105) | (n = 79) | (n = 26) | 0.026 |
< 1 × ULN | 65 (61.9) | 54 (68.4) | 11 (42.3) | |
1–2 × ULN | 25 (23.8) | 17 (21.5) | 8 (30.8) | |
2–3 × ULN | 8 (7.6) | 3 (3.8) | 5 (19.2) | |
≥3 × ULN | 7 (6.7) | 5 (6.3) | 2 (7.7) | |
AST | (n = 97) | (n = 72) | (n = 25) | 0.001 |
< 1 × ULN | 64 (66.0) | 55 (76.4) | 9 (36.0) | |
1–2 × ULN | 24 (24.7) | 13 (18.1) | 11 (44.0) | |
2–3 × ULN | 7 (7.2) | 3 (4.2) | 4 (16.0) | |
≥3 × ULN | 2 (2.1) | 1 (1.4) | 1 (4.0) | |
TBil | (n = 97) | (n = 72) | (n = 25) | 0.010 |
< 1 × ULN | 73 (75.3) | 57 (79.2) | 16 (64.0) | |
1–2 × ULN | 20 (20.6) | 15 (20.8) | 5 (20.0) | |
2–3 × ULN | 2 (2.1) | 0 (0) | 2 (8.0) | |
≥3 × ULN | 2 (2.1) | 0 (0) | 2 (8.0) | |
ALT + AST | (n = 105) | (n = 79) | (n = 26) | 0.001 |
< 1 × ULN | 83 (79.0) | 69 (87.3) | 14 (53.8) | |
1–2 × ULN | 17 (16.2) | 8 (10.1) | 9 (34.6) | |
2–3 × ULN | 3 (2.9) | 2 (2.5) | 1 (3.9) | |
≥3 × ULN | 2 (1.9) | 0 (0) | 2 (7.7) | |
ALT + TBil a | (n = 105) | (n = 79) | (n = 26) | 0.001 |
< 1 × ULN | 96 (91.4) | 77 (97.5) | 19 (73.1) | |
1–2 × ULN | 8 (7.6) | 2 (2.5) | 6 (23.1) | |
2–3 × ULN | 1 (1.0) | 0 (0) | 1 (3.8) | |
AST + TBil a | (n = 97) | (n = 72) | (n = 25) | < 0.001 |
< 1 × ULN | 88 (90.7) | 71 (98.6) | 17 (68.0) | |
1–2 × ULN | 7 (7.2) | 1 (1.4) | 6 (24.0) | |
2–3 × ULN | 2 (2.1) | 0 (0) | 2 (8.0) | |
ALT + AST + TBil a | (n = 105) | (n = 79) | (n = 26) | < 0.001 |
< 1 × ULN | 97 (92.4) | 78 (98.7) | 19 (73.1) | |
1–2 × ULN | 7 (6.7) | 1 (1.3) | 6 (23.1) | |
2–3 × ULN | 1 (1.0) | 0 (0) | 1 (3.8) | |
ALT/AST/TBil | (n = 105) | (n = 79) | (n = 26) | 0.017 |
< 1 × ULN | 46 (43.8) | 38 (48.1) | 8 (30.8) | |
1–2 × ULN | 40 (38.1) | 32 (40.5) | 8 (30.8) | |
2–3 × ULN | 10 (9.5) | 4 (5.1) | 6 (23.1) | |
≥3 × ULN | 9 (8.6) | 5 (6.3) | 4 (15.4) |