From: Ex vivo limb perfusion for traumatic amputation in military medicine
Working group | Year of publication | Characteristics |
---|---|---|
Warnecke et al. (Hannover, Germany) [14] | 2012 | Pilot study on the human application of normothermic EVP in lung transplantation |
Warnecke et al. (Hannover, Germany) [15] | 2018 | Results of the first randomized trial on the human application of normothermic EVP in lung transplantation |
Nasralla et al. (United Kingdom) [16] | 2018 | Results of the first randomized trial on normothermic EVLP in liver transplantation |
Constantinescu et al. (Bern, Switzerland) [18] | 2011 | Feasibility study of EVLP in a porcine model, 16 porcine forelimbs perfused for up to 12 h |
Müller et al. (Bern, Switzerland) [19] | 2013 | EVLP in a porcine model, 64 forelimbs perfused for up to 12 h, replantation surgery was feasible without an increased risk for IRI |
Kueckelhaus et al. (Boston, USA) [20] | 2017 | Developed a prototype hypothermic EVLP device, perfusion for 12 h with consecutive replantation in a porcine model |
Ozer et al. (Ann Arbor, USA) [21] | 2016 | Porcine model with 20 pigs and EVLP up to 24 h, feasibility of extended limb survival with normothermic EVLP |
Werner et al. (Ann Arbor, USA) [23] | 2017 | Near-normothermic EVLP in five human arms from organ donors for 24 h with shown tissue viability |
Krezdorn et al. (Boston, USA; Hannover, Germany) [24] | 2018 | Normothermic EVLP in 8 porcine forelimbs for up to 12 h with subsequent replantation, notably lower expression of hypoxia-related genes in EVLP cohort |