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Table 2 Diagnostic criteria for DIC

From: Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19

Index

Score

ISTH

CDSS

PLT (×109/L)

0

> 100

> 100

1

≤100

80–100

  

24 h decrease ≥50%

2

≤ 50

<  80

PT/APTT (s)

0

PT extension < 3

PT extension < 3 and APTT extension < 10

1

PT extension ≥3 and < 6

PT extension ≥3 or APTT extension ≥10

2

PT extension ≥6

PT extension ≥6

Fibrin-related indicators, (μg/mL)

0

DD < 2.5

 

1

–

< 5

2

Moderate increase, 2.5 ≤ DD < 5.0

5 ≤ DD < 9

3

Severe increase, DD ≥ 5.0

≥9

Fibrinogen (g/L)

0

≥1.0

≥1.0

1

< 1.0

< 1.0

Underlying disorder known to be associated with DIC

0

necessary

 

2

 

presence

 Clinical manifestation

1

 

abnormal bleeding;unexplained organ failure; shock or microcirculatory disorder (meet anyone 1 point)

Total score

 

 ≥ 5

 ≥ 7