Table 1 Underlying conditions that may cause coagulation dysfunction

Factors that increase the risk of bleeding

Hereditary coagulation factor deficiency (such as hemophilia), fibrinogen reduction, platelet deficiency, etc.

Acquired clotting factor reduction, hyperfibrinolysis, thrombocytopenia, etc.

History of taking anticoagulant or antiplatelet drugs

Diseases such as bronchiectasis, peptic ulcer, liver cirrhosis and hemorrhoids

24 h after severe trauma or surgery

Factors that cause thromboembolism

Congenital deficiency of anticoagulants (eg, antithrombin (AT) deficiency, protein C/S deficiency)

Diabetes, systemic lupus erythematosus, antiphospholipid syndrome, systemic vasculitis and other underlying diseases which have vascular endothelial cells damage

History of thrombotic diseases such as venous thrombosis, cerebral thrombosis, arterial embolism, myocardial infarction

A state of shock

Bed-ridden

Surgery

Complications with acute infections