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Table 1 Underlying conditions that may cause coagulation dysfunction

From: Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19

CauseDisease type
Factors that increase the risk of bleedingHereditary coagulation factor deficiency (such as hemophilia), fibrinogen reduction, platelet deficiency, etc.
Acquired clotting factor reduction, hyperfibrinolysis, thrombocytopenia, etc.
History of taking anticoagulant or antiplatelet drugs
Diseases such as bronchiectasis, peptic ulcer, liver cirrhosis and hemorrhoids
24 h after severe trauma or surgery
Factors that cause thromboembolismCongenital deficiency of anticoagulants (eg, antithrombin (AT) deficiency, protein C/S deficiency)
Diabetes, systemic lupus erythematosus, antiphospholipid syndrome, systemic vasculitis and other underlying diseases which have vascular endothelial cells damage
History of thrombotic diseases such as venous thrombosis, cerebral thrombosis, arterial embolism, myocardial infarction
A state of shock
Complications with acute infections