Predictors of contrast-induced acute kidney injury in patients with coronary artery disease receiving contrast agents twice within 30 days

Table 2 Agent procedural characteristics in two groups

Item	Group A (n = 559)	Group B (n = 48)	P value
TRI [n(%)]
TRI in first agent	426 (76.2)	34 (70.8)	0.404
TRI in second agent	433 (77.5)	35 (72.9)	0.472
Agents interval time [d, M(Q₁, Q₃)]^a	5 (3, 8)	4 (3, 6)	0.218
CV in 1st agent [ml, M(Q₁, Q₃)]^a	100.00 (40.00, 140.00)	90.00 (50.00, 75.00)	0.128
CV in 2nd agent[ml, M(Q₁, Q₃)]^a	150.00 (50.00, 100.00)	150.00 (50.00, 100.00)	0.334
Number of stent (x ± s)	2.23 ± 1.58	1.82 ± 1.19	0.096
Multivessel disease [n(%)]	392 (70.1)	37 (77.1)	0.310
LM lesion [n(%)]	11 (1.9)	3 (6.3)	0.091
Basic SYNTAX score (x ± s)	17.2 ± 7.5	19.2 ± 8.4	0.082
Residual SYNTAX score (x ± s)	8.8 ± 5.8	11.1 ± 7.0	0.073
Complete revascularization [n(%)]	353 (63.2)	24 (50.0)	0.072
CI-AKI post-first agent [n(%)]	41 (7.3)	15 (31.3)	< 0.001
Serum creatinine (μmol/L, x ± s)
Baseline	77.4 ± 25.0	75.1 ± 24.5	0.548
Maximal post-first agent	84.1 ± 33.9	93.7 ± 39.4	0.094
Pre-second agent	84.4 ± 56.6	81.3 ± 24.6	0.729
Maximal post-second agent	76.6 ± 27.7	100.1 ± 27.3	< 0.001

Group A No CI-AKI from second agent, Group B CI-AKI from second agent, TRI Trans-radial intervention, CV Contrast volume, LM Left main, SYNTAX Synergy between percutaneous coronary intervention with Taxus and cardiac surgery
^aMeans non-normally distributed continuous variables