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Table 5 Comparison of clinico-laboratory variables between combined Adv (cAdv), Non-Adv, and only Adv identified pathogen (OAIP) groups

From: Characteristics of fever and response to antipyretic therapy in military personnel with adenovirus-positive community-acquired pneumonia

VariablescAdv groupa (n = 30)Non-Adv group (n = 184)OAIP groupb (n = 37)P value
Age (year, M[Q1-Q3])21.5 [20.0–22.0]21.6 [20.0–22.0]21.5 [20.0–22.0]0.672
Smoking [n(%)]   < 0.001
 Never smoker21 (70.0)125 (67.9)24 (64.9) 
 Ex-smoker3 (10.0)49 (26.6)4 (10.8) 
 Current smoker6 (20.0)10 (5.4)9 (24.3) 
 Recent smoker (<  30 d)2 (6.7)0 (0)2 (5.4) 
Symptom duration(Time from symptom onset to admission) (d, x ± s)3.6 ± 1.53.2 ± 2.33.6 ± 2.00.154
Symptom and sign [n(%)]
 Fever30 (100.0)157 (85.4)36 (97.3)0.062
 Cough29 (96.7)157 (85.4)36 (97.3)0.145
 Myalgia14 (46.7)56 (30.4)17 (45.9)0.264
 Dyspnea (> mMRC scale II)3 (10.0)11 (6.1)2 (5.4)0.510
 Purulent sputum12 (40.0)58 (31.7)11 (29.7)0.126
 Headache20 (66.7)96 (52.4)28 (75.7)0.089
 Nasal congestion/rhinorrhea20 (66.7)103 (55.8)24 (64.9)0.423
WBC count (109/L, x ± s)7.54 ± 4.288.13 ± 4.054.50 ± 4.020.045
 Leukopenia (<  4 × 109/L) [n(%)]6 (20.0)10 (5.4)15 (40.5)< 0.001
 Leukocytosis (>  10 × 109/L) [n(%)]5 (16.7)52 (28.0)3 (8.1)< 0.001
 Lymphocyte (%, x ± s)23.84 ± 8.7418.62 ± 9.1520.46 ± 7.720.049
 Monocyte (%, x ± s)14.75 ± 1.6911.02 ± 3.459.35 ± 3.750.002
Platelet count (109/L, x ± s)141.4 ± 45.7184.6 ± 63.3131.2 ± 59.7< 0.001
 Thrombocytopenia (<  150 × 109/L) [n(%)]7 (23.3)17 (9.2)15 (40.5)< 0.001
Duration of fever after admission (d, x ± s)2.9 ± 1.82.0 ± 1.33.5 ± 1.40.121
Duration of fever after symptom onset (d, x ± s)5.6 ± 2.23.8 ± 2.46.0 ± 2.20.015
Mean temperature at admission day (°C, x ± s)37.8 ± 0.337.3 ± 0.337.7 ± 0.40.223
Numbers of maximal temperature at admission [n(%)]
 Over 40 °C4 (13.3)5 (2.7)6 (16.2)0.016
 39–40 °C10 (33.3)8 (4.3)14 (37.8)0.024
Responsiveness to antipyretics at admission [n(%)]   < 0.001
 Complete response16 (53.3)122 (66.3)14 (37.8) 
 Partial response12 (40.0)60 (32.6)13 (35.1) 
 No response2 (6.7)2 (1.1)10 (27.1) 
  1. Data are shown as mean ± standard deviation, median [interquartile range] or number (%)
  2. Adv Adenovirus, mMRC Modified Medical Research Council, CAP Community-acquired pneumonia
  3. acAdv defined that CAP patients with adenovirus combined other virus or bacteria as identified pathogen; bOAIP defined that CAP patients with adenovirus as the only identified pathogen
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Military Medical Research

ISSN: 2054-9369