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Table 2 Comparisons of laboratory and radiologic parameters between Adv and Non-Adv groups

From: Characteristics of fever and response to antipyretic therapy in military personnel with adenovirus-positive community-acquired pneumonia

VariablesAdv (n = 67)Non-Adv (n = 184)Total (n = 251)P value
Results of laboratory study
 WBC count (109/L)6.02 ± 4.158.13 ± 4.057.57 ± 4.080.020
  Leukopenia (<  4 × 109/L)21 (31.3)10 (5.4)31 (12.4)<  0.001
  Leukocytosis (>  10 × 109/L)8 (11.9)52 (28.0)60 (23.9)0.035
  Lymphocyte (%)22.15 ± 8.2318.62 ± 9.1519.56 ± 8.900.054
  Monocyte (%)12.05 ± 2.7211.02 ± 3.4511.49 ± 3.260.202
 Platelet count (109/L)136.3 ± 52.7184.6 ± 63.3171.7 ± 61.2<  0.001
  Thrombocytopenia (<  150 × 109/L)22 (32.8)17 (9.2)39 (15.5)<  0.001
 Total bilirubin (mg/dl)0.6 ± 0.30.6 ± 0.20.6 ± 0.20.715
 Creatinine (mg/dl)0.57 ± 0.140.64 ± 0.140.62 ± 0.140.442
 C-reactive protein (mg/dl)5.24 ± 2.946.02 ± 3.116.00 ± 3.050.411
 Procalcitonin (ng/ml)0.04 [0.00–0.08]0.06 [0.00–0.10]0.05 [0.00–0.08]0.635
Results of etiologic study [n(%)]
 Unknown pathogenNA50 (27.2)50 (20.0)NA
 Viral etiology[n(%)]   <  0.001
  Adv67 (100)NA67 (26.7)NA
  Rhinovirus5 (7.5)18 (9.8)23 (9.2) 
  Influenza A/B virus4 (6.0)22 (12.0)26 (10.4) 
  HMPV(−)1 (0.5)1 (0.4) 
  RSV1 (1.5)3 (1.6)4 (1.6) 
  Parainfluenza virus1 (1.5)3 (1.6)4 (1.6) 
 Bacterial etiology [n(%)]   <  0.001
S. pneumoniae3 (4.5)19 (10.3)22 (8.8) 
H. influenzae3 (4.5)12 (6.5)15 (6.0) 
M. pneumoniae5 (7.5)8 (4.3)13 (5.2) 
K. pneumoniae(−)2 (1.1)2 (0.8) 
Combined etiologies [n(%)]   <  0.001
S. pneumonia plus H.pneumoniae7 (10.4)14 (7.6)21 (8.4) 
  Rhinovirus plus H.pneumoniae(−)22 (12.0)22 (8.8) 
  Influenza A/B virus plus S.pneumoniae1 (1.5)6 (3.3)7 (2.8) 
  Influenza A/B virus plus H.influenzae(−)2 (1.1)2 (0.8) 
  RSV plus H.influenzae(−)2 (1.1)2 (0.8) 
Results of radiologic study
 Dominant pattern [n(%)]   <  0.001
  GGO3(4.5)6 (3.3)9 (3.6) 
  Consolidation23 (24.3)103 (56.0)126 (50.2) 
  GGO plus consolidation41 (61.2)75 (40.7)116 (46.2) 
Distribution [n(%)]   0.015
  Unilateral56 (83.5)133 (72.2)189 (75.3) 
  Bilateral5 (7.5)10 (5.4)15 (6.0) 
  Multi-lobar (≥ 3 lobes)6 (9.0)41 (22.3)47 (18.7) 
 Pleural effusion [n(%)]2 (3.0)8 (4.3)10 (4.0)0.483
  1. Data are shown as mean ± standard deviation, median [interquartile range] or number (%)
  2. NA Not available, Adv Adenovirus, RSV Respiratory syncytial virus, HMPV Human metapneumovirus, GGO Ground glass opacity, S. pneumoniae Streptococcus pneumoniae, H. influenzae Haemophilus influenzae, M. pneumoniae Mycoplasma pneumoniae, K. pneumoniae Klebsiella pneumoniae
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Military Medical Research

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