Table 2 Comparisons of laboratory and radiologic parameters between Adv and Non-Adv groups
Variables | Adv (n = 67) | Non-Adv (n = 184) | Total (n = 251) | P value |
|---|---|---|---|---|
Results of laboratory study | ||||
WBC count (109/L) | 6.02 ± 4.15 | 8.13 ± 4.05 | 7.57 ± 4.08 | 0.020 |
Leukopenia (< 4 × 109/L) | 21 (31.3) | 10 (5.4) | 31 (12.4) | < 0.001 |
Leukocytosis (> 10 × 109/L) | 8 (11.9) | 52 (28.0) | 60 (23.9) | 0.035 |
Lymphocyte (%) | 22.15 ± 8.23 | 18.62 ± 9.15 | 19.56 ± 8.90 | 0.054 |
Monocyte (%) | 12.05 ± 2.72 | 11.02 ± 3.45 | 11.49 ± 3.26 | 0.202 |
Platelet count (109/L) | 136.3 ± 52.7 | 184.6 ± 63.3 | 171.7 ± 61.2 | < 0.001 |
Thrombocytopenia (< 150 × 109/L) | 22 (32.8) | 17 (9.2) | 39 (15.5) | < 0.001 |
Total bilirubin (mg/dl) | 0.6 ± 0.3 | 0.6 ± 0.2 | 0.6 ± 0.2 | 0.715 |
Creatinine (mg/dl) | 0.57 ± 0.14 | 0.64 ± 0.14 | 0.62 ± 0.14 | 0.442 |
C-reactive protein (mg/dl) | 5.24 ± 2.94 | 6.02 ± 3.11 | 6.00 ± 3.05 | 0.411 |
Procalcitonin (ng/ml) | 0.04 [0.00–0.08] | 0.06 [0.00–0.10] | 0.05 [0.00–0.08] | 0.635 |
Results of etiologic study [n(%)] | ||||
Unknown pathogen | NA | 50 (27.2) | 50 (20.0) | NA |
Viral etiology[n(%)] | < 0.001 | |||
Adv | 67 (100) | NA | 67 (26.7) | NA |
Rhinovirus | 5 (7.5) | 18 (9.8) | 23 (9.2) | |
Influenza A/B virus | 4 (6.0) | 22 (12.0) | 26 (10.4) | |
HMPV | (−) | 1 (0.5) | 1 (0.4) | |
RSV | 1 (1.5) | 3 (1.6) | 4 (1.6) | |
Parainfluenza virus | 1 (1.5) | 3 (1.6) | 4 (1.6) | |
Bacterial etiology [n(%)] | < 0.001 | |||
S. pneumoniae | 3 (4.5) | 19 (10.3) | 22 (8.8) | |
H. influenzae | 3 (4.5) | 12 (6.5) | 15 (6.0) | |
M. pneumoniae | 5 (7.5) | 8 (4.3) | 13 (5.2) | |
K. pneumoniae | (−) | 2 (1.1) | 2 (0.8) | |
Combined etiologies [n(%)] | < 0.001 | |||
S. pneumonia plus H.pneumoniae | 7 (10.4) | 14 (7.6) | 21 (8.4) | |
Rhinovirus plus H.pneumoniae | (−) | 22 (12.0) | 22 (8.8) | |
Influenza A/B virus plus S.pneumoniae | 1 (1.5) | 6 (3.3) | 7 (2.8) | |
Influenza A/B virus plus H.influenzae | (−) | 2 (1.1) | 2 (0.8) | |
RSV plus H.influenzae | (−) | 2 (1.1) | 2 (0.8) | |
Results of radiologic study | ||||
Dominant pattern [n(%)] | < 0.001 | |||
GGO | 3(4.5) | 6 (3.3) | 9 (3.6) | |
Consolidation | 23 (24.3) | 103 (56.0) | 126 (50.2) | |
GGO plus consolidation | 41 (61.2) | 75 (40.7) | 116 (46.2) | |
Distribution [n(%)] | 0.015 | |||
Unilateral | 56 (83.5) | 133 (72.2) | 189 (75.3) | |
Bilateral | 5 (7.5) | 10 (5.4) | 15 (6.0) | |
Multi-lobar (≥ 3 lobes) | 6 (9.0) | 41 (22.3) | 47 (18.7) | |
Pleural effusion [n(%)] | 2 (3.0) | 8 (4.3) | 10 (4.0) | 0.483 |