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Table 3 Main target genes of the differentially expressed miRNAs in the 48-h group compared with 2-h group

From: Dynamic changes in peripheral blood-targeted miRNA expression profiles in patients with severe traumatic brain injury at high altitude

Change in miRNA expression

Name of miRNA

Predicted target genes

Upregulated

miR-181d

Zinc finger protein 594; zinc finger protein 440

miR-29a

ATPase family AAA domain-containing protein 2B; peptidase inhibitor 15

miR-18b

Neural precursor cells expressed; developmentally regulated protein 9; glycine receptor

miR-132

Transmembrane protein 106B; zinc finger protein 516

miR-let-7b

High mobility group AT-hook 2; chromosome 14 open reading frame 28

Downregulated

miR-181c

Modulates the proliferation, migration, and invasion of neuroblastoma cells by targeting Smad7

miR-214

NMDA receptor-regulated 2; κ-opioid receptor