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Table 4 Effects of methazolamide and BW on hypoxic tolerance indices in mice (\( \overline{x} \)±s)

From: An improved formula for standard hypoxia tolerance time (STT) to evaluate hypoxic tolerance in mice

Group

BW (g)

Bottle volume (ml)

ST (min)

STT (min/ml)

ASTT (min·g/ml)

Saline (n = 13)

18.31 ± 0.60

158 ± 2.8

15.12 ± 2.06

0.11 ± 0.0146

2.00 ± 0.283

Methazolamide 1 (Medium BW) (n = 13)

18.68 ± 0.68

158 ± 2.8

20.62 ± 3.17

0.15 ± 0.0218*

2.78 ± 0.367*

Methazolamide 2 (High BW) (n = 13)

22.59 ± 1.03*

158 ± 2.8

16.22 ± 3.29

0.12 ± 0.0241△

2.73 ± 0.457*

  1. ST. Survival time; STT. Standard hypoxia tolerance time; ASTT. Adjusted standard hypoxia tolerance time; BW. Body weight. * P < 0.01 compared with saline group; △ P < 0.01 compared with methazolamide group 1 (medium BW)
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Military Medical Research

ISSN: 2054-9369