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Table 6 Effect of cimetidine on MDA in serum and hepatic tissues of n-γ LDR rats (x ± s, n = 10)

From: Radioprotective effects of cimetidine on rats irradiated by long-term, low-dose-rate neutrons and 60Co γ-rays

Group

MDA in serum (nmol/ml)

MDA in hepatic tissue (nmol/mg protein)

Normal control group

3.67 ± 0.431

4.18 ± 0.60

Radiation model group

4.02 ± 0.37(2)

4.89 ± 0.28(1)

20 mg/(kg · d) cimetidine group

3.70 ± 0.36(3)

4.34 ± 0.29(4)

80 mg/(kg · d) cimetidine group

3.83 ± 0.40

4.35 ± 0.53(3)

160 mg/(kg · d) cimetidine group

3.50 ± 0.38(4)

4.27 ± 0.30(4)

  1. (1) P < 0.05, (2) P < 0.01compared with the normal control group; (3) P < 0.05, (4) P < 0.01 compared with the radiation model group