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Table 6 Effect of cimetidine on MDA in serum and hepatic tissues of n-γ LDR rats (x ± s, n = 10)

From: Radioprotective effects of cimetidine on rats irradiated by long-term, low-dose-rate neutrons and 60Co γ-rays

Group MDA in serum (nmol/ml) MDA in hepatic tissue (nmol/mg protein)
Normal control group 3.67 ± 0.431 4.18 ± 0.60
Radiation model group 4.02 ± 0.37(2) 4.89 ± 0.28(1)
20 mg/(kg · d) cimetidine group 3.70 ± 0.36(3) 4.34 ± 0.29(4)
80 mg/(kg · d) cimetidine group 3.83 ± 0.40 4.35 ± 0.53(3)
160 mg/(kg · d) cimetidine group 3.50 ± 0.38(4) 4.27 ± 0.30(4)
  1. (1) P < 0.05, (2) P < 0.01compared with the normal control group; (3) P < 0.05, (4) P < 0.01 compared with the radiation model group