Radioprotective effects of cimetidine on rats irradiated by long-term, low-dose-rate neutrons and 60Co γ-rays

Table 4 Effect of cimetidine on SOD activity in serum and hepatic tissues of n-γ LDR rats (x ± s, n = 10)

Group	SOD in serum (U/ml)	SOD in hepatic tissue (U/mg protein)
Normal control group	20.22 ± 0.94	174.01 ± 20.84
Radiation model group	15.04 ± 1.60⁽²⁾	142.99 ± 4.03⁽²⁾
20 mg/(kg · d) cimetidine group	19.75 ± 5.39⁽⁴⁾	184.25 ± 7.59⁽⁴⁾
80 mg/(kg · d) cimetidine group	16.26 ± 3.60⁽¹⁾	137.87 ± 26.99⁽²⁾⁽⁵⁾
160 mg/(kg · d) cimetidine group	17.47 ± 2.13⁽²⁾⁽³⁾	141.59 ± 11.04⁽²⁾⁽⁵⁾

⁽¹⁾ P < 0.05, ⁽²⁾ P < 0.01 compared with the normal control group; ⁽³⁾ P < 0.05, ⁽⁴⁾ P < 0.01 compared with the radiation model group; ⁽⁵⁾ P < 0.05 compared with the 20 mg/(kg · d) cimetidine group

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