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Table 4 Effect of cimetidine on SOD activity in serum and hepatic tissues of n-γ LDR rats (x ± s, n = 10)

From: Radioprotective effects of cimetidine on rats irradiated by long-term, low-dose-rate neutrons and 60Co γ-rays

Group SOD in serum (U/ml) SOD in hepatic tissue (U/mg protein)
Normal control group 20.22 ± 0.94 174.01 ± 20.84
Radiation model group 15.04 ± 1.60(2) 142.99 ± 4.03(2)
20 mg/(kg · d) cimetidine group 19.75 ± 5.39(4) 184.25 ± 7.59(4)
80 mg/(kg · d) cimetidine group 16.26 ± 3.60(1) 137.87 ± 26.99(2)(5)
160 mg/(kg · d) cimetidine group 17.47 ± 2.13(2)(3) 141.59 ± 11.04(2)(5)
  1. (1) P < 0.05, (2) P < 0.01 compared with the normal control group; (3) P < 0.05, (4) P < 0.01 compared with the radiation model group; (5) P < 0.05 compared with the 20 mg/(kg · d) cimetidine group