Radioprotective effects of cimetidine on rats irradiated by long-term, low-dose-rate neutrons and 60 Co γ-rays

Table 3 Effect of cimetidine on the organ indexes of n-γ LDR rats (mg/g, x ± s, n = 10)

Group	Spleen index	Thymus index	Testicle index	Liver index	Intestinal tract index
Normal control group	2.16 ± 0.21	1.75 ± 0.14	8.20 ± 0.83	33.75 ± 4.01	0.38 ± 0.03
Radiation model group	1.74 ± 0.22⁽²⁾	1.41 ± 0.26⁽¹⁾	7.44 ± 0.46⁽¹⁾	32.81 ± 1.63	0.37 ± 0.03
20 mg/(kg · d) cimetidine group	2.02 ± 0.23⁽⁴⁾	1.69 ± 0.29⁽³⁾	7.88 ± 0.58	32.03 ± 1.24	0.38 ± 0.02
80 mg/(kg · d) cimetidine group	1.89 ± 0.21⁽¹⁾	1.64 ± 0.31	7.60 ± 0.61	31.63 ± 2.15	0.38 ± 0.02
160 mg/(kg · d) cimetidine group	1.91 ± 0.14⁽²⁾⁽³⁾	1.63 ± 0.29	7.94 ± 0.49⁽³⁾	34.34 ± 3.25	0.39 ± 0.03

⁽¹⁾ P < 0.05, ⁽²⁾ P < 0.01 compared with the normal control group; ⁽³⁾ P < 0.05, ⁽⁴⁾ P < 0.01 compared with the radiation model group

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