Group
|
3rd day before IR
|
8th day
|
17th day
|
26th day
|
---|
Normal control group
|
10.9 ± 1.6
|
11.6 ± 1.2
|
10.7 ± 1.2
|
10.0 ± 2.6
|
Radiation model group
|
10.8 ± 2.2
|
7.7 ± 1.0(1)
|
8.2 ± 2.3(1)
|
6.3 ± 0.7(1)
|
20 mg/(kg · d) cimetidine group
|
10.7 ± 1.5
|
11.3 ± 2.1(3)
|
8.6 ± 1.3(1)
|
7.2 ± 1.2(1)(2)(4)
|
80 mg/(kg · d) cimetidine group
|
10.6 ± 1.7
|
9.0 ± 1.6(1)(2)
|
7.9 ± 1.1(1)
|
7.2 ± 1.0(1)(2)(4)
|
160 mg/(kg · d) cimetidine group
|
10.5 ± 1.5
|
9.0 ± 1.9(1)
|
8.4 ± 1.2(1)
|
5.8 ± 1.2(1)
|
-
(1)
P < 0.01 compared with the normal control group; (2)
P < 0.05, (3)
P < 0.01 compared with the radiation model group; (4)
P < 0.05 compared with the 160 mg/(kg · d) cimetidine group. The 8th, 17th and 26th day were the days that the rats were exposed to n-γ LDR for 7, 16 and 25 days, respectively