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Table 5 AEs during 180-day follow-up

From: Effects of omeprazole or pantoprazole on platelet function in non-ST-segment elevation acute coronary syndrome patients receiving clopidogrel

Characteristic

Omeprazole group (n = 303)

Pantoprazole group (n = 304)

P value

Stent thrombosis [n (%)]

0

0

MACEs [n (%)]

8 (2.6)

7 (2.3)

0.80

 Cardiac death

1 (0.3)

0

0.50

 Myocardial infarction

0

0

 Ischemic symptoms driven target vessel revascularization

3 (1.0)

1 (0.3)

0.37

 Non-target vessel revascularization

6 (2.0)

6 (2.0)

1.00

Recurrent angina [n (%)]

30 (9.9)

24 (7.9)

0.40

All-cause death [n (%)]

1 (0.3)a

1 (0.3)b

1.00

TIMI bleeding evens [n (%)]

15 (5.0)

19 (6.3)

0.60

 Major

0

1 (0.3)

1.00

 Moderate

0

3 (1.0)

0.25

 Minor

16 (5.3)

14 (4.6)

0.71

Stroke [n (%)]

1 (0.3)

0

0.50

Adverse drug reactions [n (%)]

17 (5.6)

19 (6.3)

0.86

AEs [n (%)]

50 (16.5)

44 (14.5)

0.50

  1. aOne patient died due to lung cancer in the omeprazole group
  2. bOne patient died due to acute brainstem hemorrhage in the pantoprazole group