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Table 3 Contribution of CYP450 isozyme to T-2 toxin hepatic metabolism assessed by the TNR method

From: The roles of carboxylesterase and CYP isozymes on the in vitro metabolism of T-2 toxin

CYP isozyme type CYP2C19 CYP 3A4 CYP2C9 CYP2B6 CYP2D6 CYP1A2 CYP2E1
Vm (nmol/T-2/min nmol protein) 0.86 ± 0.02 13.98 ± 3.46 0.47 ± 0.03 1.2 ± .02 1.73 ± 0.03 1.37 ± 0.05 1.41 ± 0.07
Percentage of total activity 0.63 89.70 1.72 0.69 0.63 3.01 3.62