Figure 2From: Effects and mechanisms of a microcurrent dressing on skin wound healing: a reviewThe BMP/SMAD signaling pathway. In the pathway, the interaction of BMP6 dimers with their receptors leads to the activation of the receptor kinase, followed by the phosphorylation of SMAD1/5/8 and the formation of the SMAD1/5/8-SMAD4 complex, which, when translocated to the nucleus, activates the promoters of the target genes and then regulates SMAD7 and ID1.Back to article page